DILATED CARDIOMYOPATHY (DCM)
Clinical trials for DILATED CARDIOMYOPATHY (DCM) explained in plain language.
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First-in-Human gene therapy trial aims to fix faulty heart genes
Disease control Not yet recruitingThis is a very early study testing the safety of a new gene therapy for adults with a specific inherited form of heart muscle weakness (dilated cardiomyopathy). The therapy, called RP-A701, is given as a single intravenous dose and aims to deliver a working copy of a faulty gene …
Matched conditions: DILATED CARDIOMYOPATHY (DCM)
Phase: PHASE1 • Sponsor: Rocket Pharmaceuticals Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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First human trial for gene therapy targeting rare heart disease
Disease control Not yet recruitingThis early-stage trial is testing a new, single-dose gene therapy called AFTX-201 for adults with a specific inherited form of heart failure. The main goal is to see if the treatment is safe and well-tolerated. Researchers will also look for early signs that it might improve hear…
Matched conditions: DILATED CARDIOMYOPATHY (DCM)
Phase: PHASE1, PHASE2 • Sponsor: Affinia Therapeutics • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Scientists try to regrow damaged hearts with stem cells
Disease control Not yet recruitingThis early-stage study is testing whether transplanting tiny spheres of lab-grown heart muscle cells can help people with severe heart failure. Fourteen patients will receive the cells via a catheter to their heart and be monitored for safety and potential improvements in heart f…
Matched conditions: DILATED CARDIOMYOPATHY (DCM)
Phase: PHASE1, PHASE2 • Sponsor: Heartseed Inc. • Aim: Disease control
Last updated Mar 09, 2026 14:26 UTC
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Cutting 3-Year wait for heart failure genetic tests
Diagnosis Not yet recruitingThis study aims to help heart failure patients in British Columbia and Alberta get genetic testing faster by training heart clinic doctors to order these tests directly. Currently, patients must wait up to three years to see a genetics specialist for testing that can identify inh…
Matched conditions: DILATED CARDIOMYOPATHY (DCM)
Phase: NA • Sponsor: Thomas Roston • Aim: Diagnosis
Last updated Mar 19, 2026 14:55 UTC
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Scientists track rare genetic heart condition in 30 patients worldwide
Knowledge-focused Not yet recruitingThis study aims to learn how a specific inherited form of heart muscle disease (dilated cardiomyopathy) progresses over time in adults who have a harmful change in their BAG3 gene. Researchers will follow about 30 patients to document their symptoms, heart function, and quality o…
Matched conditions: DILATED CARDIOMYOPATHY (DCM)
Sponsor: Rocket Pharmaceuticals Inc. • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC