DEMORALIZATION
Clinical trials for DEMORALIZATION explained in plain language.
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LSD trial aims to ease End-of-Life distress
Symptom relief Recruiting nowThis study tests whether low or moderate doses of LSD can reduce anxiety, pain, and depression in people with advanced or terminal illnesses. Sixty participants will receive either two moderate doses or two very low (placebo-like) doses of LSD in a double-blind setup. The goal is…
Matched conditions: DEMORALIZATION
Phase: PHASE2 • Sponsor: University Hospital, Basel, Switzerland • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Magic mushroom compound may ease despair in advanced cancer patients
Symptom relief Recruiting nowThis pilot study tests whether psilocybin (the active ingredient in magic mushrooms) combined with talk therapy can safely reduce demoralization in people with advanced cancer. Fifteen participants aged 18-70 will receive one 25 mg dose of psilocybin during an 8-hour supervised s…
Matched conditions: DEMORALIZATION
Phase: PHASE1 • Sponsor: Gustavo Vazquez • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Psychedelic drug could lift spirits in final years
Symptom relief Recruiting nowThis phase 2 trial tests whether psilocybin therapy can reduce demoralization in adults with a life expectancy of two years or less. One hundred participants will receive either psilocybin or an active control (ketamine) in a triple-blind design. The goal is to see if this approa…
Matched conditions: DEMORALIZATION
Phase: PHASE2 • Sponsor: Charles S. Grob, M.D. • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC