DCIS
Clinical trials for DCIS explained in plain language.
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Radiation-Free future? trial tests if some breast cancer patients can safely skip treatment
Disease control OngoingThis study is testing whether women with a specific, very low-risk type of early breast cancer (DCIS) can safely skip whole-breast radiation after breast-conserving surgery. It aims to identify patients who are unlikely to have the cancer return, allowing them to avoid the side e…
Matched conditions: DCIS
Phase: NA • Sponsor: UNICANCER • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Could avoiding surgery be safer for some breast cancer patients?
Disease control OngoingThis large study is testing whether active monitoring (watchful waiting) is as safe and effective as surgery for women with a very early, low-risk form of breast cancer called DCIS. It aims to see if avoiding surgery can prevent unnecessary treatment and side effects like chronic…
Matched conditions: DCIS
Phase: NA • Sponsor: Alliance Foundation Trials, LLC. • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Radiation first: new approach aims for better breast cancer results
Disease control TerminatedThis study is testing whether giving targeted radiation to part of the breast before surgery is a safe and feasible approach for early-stage breast cancer. It will enroll about 98 patients to see if this timing leads to fewer wound problems and better cosmetic outcomes compared t…
Matched conditions: DCIS
Phase: PHASE1 • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Mar 19, 2026 14:55 UTC
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Glowing dye lights up cancer cells during surgery
Diagnosis OngoingThis study is testing a new fluorescent dye called LS301-IT. It is given by IV before surgery to help surgeons see the edges of breast cancer tissue and nearby lymph nodes more clearly. The main goals are to check if the dye is safe and to see how well it helps guide surgery for …
Matched conditions: DCIS
Phase: PHASE1, PHASE2 • Sponsor: Integro Theranostics • Aim: Diagnosis
Last updated Mar 23, 2026 15:19 UTC
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Could many women safely skip breast cancer surgery? major trial tests 'Watch and Wait' approach
Knowledge-focused OngoingThis study aims to find out if a 'watchful waiting' approach is as safe as immediate surgery or radiation for women with certain early, non-invasive breast cell changes (low-risk DCIS). It will follow 2,500 women for 10 years, comparing those who choose active monitoring with ann…
Matched conditions: DCIS
Phase: NA • Sponsor: The Netherlands Cancer Institute • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC