CYTOKINE RELEASE SYNDROME
Clinical trials for CYTOKINE RELEASE SYNDROME explained in plain language.
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New drug may tame Life-Threatening side effects of cancer immunotherapy
Disease control CompletedThis study tested whether the drug siltuximab can lessen the severity of cytokine release syndrome (CRS) and neurological side effects (ICANS) that often occur after CAR-T cell therapy for blood cancers like lymphoma and leukemia. Twenty-four participants received siltuximab alon…
Matched conditions: CYTOKINE RELEASE SYNDROME
Phase: PHASE2 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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Can a common arthritis drug tame CAR-T's dangerous side effects?
Symptom relief CompletedThis phase 2 trial tested whether adding the drug anakinra (Kineret) to standard CAR-T cell therapy could prevent nerve toxicity in 15 people with relapsed or refractory non-Hodgkin lymphoma. Participants received anakinra injections for a week alongside their CAR-T infusion. The…
Matched conditions: CYTOKINE RELEASE SYNDROME
Phase: PHASE2 • Sponsor: Marcela V. Maus, M.D.,Ph.D. • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC