CRITICALLY ILL
Clinical trials for CRITICALLY ILL explained in plain language.
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Can vitamin d shield kidneys in the ICU? new study investigates
Disease control CompletedThis study tested whether two forms of activated vitamin D (calcifediol and calcitriol) could prevent or reduce the severity of acute kidney injury in critically ill patients. Researchers enrolled 150 adults in the ICU who were at high risk for kidney damage. The goal was to see …
Matched conditions: CRITICALLY ILL
Phase: PHASE2 • Sponsor: David Leaf • Aim: Disease control
Last updated May 11, 2026 20:52 UTC
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Protein boost for sick kids: could it speed recovery?
Knowledge-focused CompletedThis pilot study tested whether giving extra protein to underweight children in intensive care could help them recover faster. The study included 34 children and focused on whether the approach was practical for a larger trial. Key measures included how many families agreed to jo…
Matched conditions: CRITICALLY ILL
Phase: NA • Sponsor: KK Women's and Children's Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 11:08 UTC
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Can steady cuff pressure stop hidden lung infections in ICU patients?
Knowledge-focused CompletedThis study looked at whether keeping steady pressure on the breathing tube's cuff (the balloon that seals the airway) can reduce stomach fluid from leaking into the windpipe in critically ill patients. Researchers measured a stomach enzyme in lung fluids from 122 adults on breath…
Matched conditions: CRITICALLY ILL
Phase: PHASE4 • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 17, 2026 11:08 UTC
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Fast bug test aims to speed up right antibiotics for ICU pneumonia
Knowledge-focused CompletedThis study tested whether a rapid test (BioFire FA Pneumonia Panel) can help doctors choose the right antibiotics faster for ICU patients on breathing machines who have suspected pneumonia. 40 adults were randomly assigned to get either the rapid test or standard care. The main g…
Matched conditions: CRITICALLY ILL
Phase: PHASE2 • Sponsor: Chinese University of Hong Kong • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Anemia duration may predict ventilator needs in critically ill patients
Knowledge-focused CompletedThis study examined 236 adults in the surgical intensive care unit who needed a breathing machine for more than 4 days. Researchers wanted to see if the length of time a patient had anemia (low red blood cells) was related to how long they needed the breathing machine. The goal w…
Matched conditions: CRITICALLY ILL
Sponsor: Mahidol University • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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French ICUs under the microscope: what happens to the sickest COVID-19 patients?
Knowledge-focused CompletedThis study looked at over 1,000 adults with COVID-19 who were admitted to intensive care units (ICUs) in France. Researchers tracked their care and outcomes, such as death within 28 days and serious complications like kidney injury or blood clots. The goal was to understand how t…
Matched conditions: CRITICALLY ILL
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Global experts unite to clear the air on ICU breathing tube care
Knowledge-focused CompletedThis study brought together 35 healthcare experts from around the world to agree on the best methods for clearing mucus from the airways of critically ill patients who are on breathing machines. The goal was to create clear, practical guidelines for treatments like humidification…
Matched conditions: CRITICALLY ILL
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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Simple tool may improve First-Attempt success for emergency breathing tubes
Knowledge-focused CompletedThis study looked at whether using a bendable wire (stylet) inside the breathing tube helps doctors place the tube correctly on the first try in critically ill patients. Over 1,000 adults in intensive care who needed emergency breathing support took part. The goal was to see if t…
Matched conditions: CRITICALLY ILL
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated May 06, 2026 16:01 UTC
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Doctors test better way to measure kidney health in critically ill patients
Knowledge-focused CompletedThis study compared two different methods for measuring kidney function in critically ill ICU patients whose kidneys work unusually fast. Researchers tested 90 ICU patients to see if a newer test using a special dye (iohexol) gives more accurate results than the standard creatini…
Matched conditions: CRITICALLY ILL
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Apr 22, 2026 15:58 UTC