CORONA VIRUS INFECTION

This study tested the CoviVac COVID-19 vaccine in 200 healthy adults aged 60 and older. Researchers checked how safe the vaccine was and how well it boosted the immune system. The goal was to see if the vaccine could help prevent COVID-19 in this age group.

This study tested three new self-amplifying RNA vaccines against COVID-19 in 72 healthy adults, some already vaccinated and some not. The goal was to check safety and how well the vaccines boost the immune system. Results help decide which vaccine candidates to study further.

This study tests an experimental drug called SPI-1005 (ebselen) in adults hospitalized with severe COVID-19. Participants receive either the drug or a placebo to see if the drug is safe and helps improve recovery. The trial is randomized and double-blind, meaning neither patients…

This large, completed trial tested several potential COVID-19 treatments in over 1,500 hospitalized adults across Europe. Earlier drugs like remdesivir and hydroxychloroquine were dropped after showing no benefit. The current phase is testing a new antibody combination called AZD…

This study tested whether giving early treatment to adults with COVID-19 who have risk factors (like age over 60 or high blood pressure) could prevent them from needing oxygen, hospitalization, or dying. About 412 people took part. The goal was to see if these treatments are safe…

This early-stage study tested a new drug called SIR1-365 in 45 hospitalized adults with severe COVID-19. The main goal was to see if the drug is safe and tolerable. Researchers also looked at whether it could reduce inflammation and improve patient outcomes. The trial was complet…

This phase 3 study tested the drug sarilumab (Kevzara®) in 420 adults hospitalized with severe or critical COVID-19. Participants received either sarilumab or a placebo by IV. The main goal was to see if sarilumab speeds up clinical improvement. The trial also tracked survival, n…

This early-stage trial tested an oral drug called SAR443122 in 68 hospitalized adults with severe COVID-19. The goal was to see if the drug could safely reduce harmful inflammation, measured by a blood marker called CRP. Participants were randomly assigned to receive the drug or …

This study looked at children and young adults under 24 who had COVID-19, including those with cancer. Researchers collected samples and medical information to learn about symptoms, risk factors, and how the virus spreads. The goal was to better understand the disease in younger …

This study looked at whether it is safe to give another dose of a COVID-19 mRNA vaccine to people who had a bad reaction to a previous dose, or to people with a history of allergies. It also included people with long COVID. A total of 137 adults took part and received either the …

This study looked at nearly 2,000 adults with lung cancer who caught COVID-19. Researchers tracked their health and checked for antibodies (immune system markers) right after infection and again 6 months after vaccination. The goal was to understand how lung cancer affects the bo…

This study looked at how T-cells, a key part of the immune system, respond to the COVID-19 virus in 51 people—hospitalized patients and healthy hospital staff. Researchers measured T-cell activity at several time points using a blood test called ELISPOT. The goal was to better un…

This completed registry study collected data from 500 COVID-19 patients to learn how the virus affects kidney function. Researchers aimed to identify risk factors and track outcomes. The findings may help guide future treatment and care for kidney complications in COVID-19.

This study followed over 1,000 adults with confirmed or suspected COVID-19 who were admitted to intensive care units (ICUs) across France. Researchers tracked their treatments, complications, and survival at 28 days. The goal was to learn how these patients are managed and what f…

This study followed 211 older adults who were hospitalized with COVID-19 to see how their mobility and daily function changed over time. Researchers measured physical abilities like walking, balance, and thinking skills. The goal is to understand recovery patterns so doctors can …