CORONA VIRUS INFECTION
Clinical trials for CORONA VIRUS INFECTION explained in plain language.
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New Self-Amplifying RNA vaccines show promise in early COVID-19 trial
⭐️ VACCINE ⭐️ CompletedThis early-stage study tested three new self-amplifying RNA vaccines against COVID-19 in 72 healthy adults, some already vaccinated and some not. The main goal was to check safety and how well the vaccines triggered an immune response. Results help researchers decide which vaccin…
Matched conditions: CORONA VIRUS INFECTION
Phase: PHASE1, PHASE2 • Sponsor: Arcturus Therapeutics, Inc. • Aim: ⭐️ VACCINE ⭐️
Last updated May 15, 2026 11:53 UTC
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New COVID-19 vaccine tested in seniors shows promise
⭐️ VACCINE ⭐️ CompletedThis study tested the CoviVac vaccine in 200 adults aged 60 and older to see if it safely prevents COVID-19. Researchers measured side effects and immune response after two doses. The goal was to check if the vaccine works well for older adults, who are at higher risk from the vi…
Matched conditions: CORONA VIRUS INFECTION
Phase: PHASE2 • Sponsor: Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products • Aim: ⭐️ VACCINE ⭐️
Last updated May 14, 2026 12:02 UTC
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COVID drug sarilumab fails to deliver breakthrough in severe cases
Disease control CompletedThis study tested a drug called sarilumab in 420 adults hospitalized with severe or critical COVID-19. The goal was to see if it could help patients recover faster and improve survival. Sarilumab works by calming an overactive immune response, but it is not a cure and patients ma…
Matched conditions: CORONA VIRUS INFECTION
Phase: PHASE3 • Sponsor: Sanofi • Aim: Disease control
Last updated May 17, 2026 03:10 UTC
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New COVID-19 drug SIR1-365 tested for safety in hospitalized patients
Disease control CompletedThis early-stage trial tested the safety of an experimental drug called SIR1-365 in 45 hospitalized adults with severe COVID-19. Participants received either the drug or a placebo, and researchers monitored side effects and signs of inflammation. The goal was to see if the drug i…
Matched conditions: CORONA VIRUS INFECTION
Phase: PHASE1 • Sponsor: Sironax USA, Inc. • Aim: Disease control
Last updated May 17, 2026 03:00 UTC
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Experimental drug aims to tame COVID-19's deadly inflammation
Disease control CompletedThis early-stage study tested an experimental drug called SAR443122 in 68 hospitalized adults with severe COVID-19. The goal was to see if the drug could safely reduce dangerous inflammation, measured by a blood marker called CRP. Participants received either the drug or a placeb…
Matched conditions: CORONA VIRUS INFECTION
Phase: PHASE1 • Sponsor: Sanofi • Aim: Disease control
Last updated May 12, 2026 13:39 UTC
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Scientists track Body's Virus-Fighting cells in COVID patients
Knowledge-focused CompletedThis study looked at how the immune system's T-cells respond to the COVID-19 virus in hospitalized patients. Researchers measured the number of T-cells that produce a key immune signal (interferon-gamma) when exposed to the virus's spike protein. The goal was to better understand…
Matched conditions: CORONA VIRUS INFECTION
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated May 17, 2026 03:12 UTC
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Hidden toll of COVID-19: seniors' mobility after hospital stay under the microscope
Knowledge-focused CompletedThis study followed 211 older adults who were hospitalized with COVID-19 to see how their ability to move and do daily tasks changed over time. Researchers measured mobility, thinking skills, and frailty at several points after discharge. The goal is to understand the long road t…
Matched conditions: CORONA VIRUS INFECTION
Sponsor: McMaster University • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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New study reveals how COVID-19 affects kids
Knowledge-focused CompletedThis study aimed to learn more about how COVID-19 affects children, especially those with cancer. Researchers collected samples from 33 children to study symptoms, risk factors, and how long the virus lasts. The goal was to improve detection and treatment for kids in the future.
Matched conditions: CORONA VIRUS INFECTION
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated May 15, 2026 11:52 UTC
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French ICUs under the microscope: what happens to the sickest COVID-19 patients?
Knowledge-focused CompletedThis study looked at over 1,000 adults with COVID-19 who were admitted to intensive care units (ICUs) in France. Researchers tracked their care and outcomes, such as death within 28 days and serious complications like kidney injury or blood clots. The goal was to understand how t…
Matched conditions: CORONA VIRUS INFECTION
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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COVID-19's hidden toll on kidneys revealed in global registry
Knowledge-focused CompletedThis study collected health information from 500 people with confirmed COVID-19 to understand how the virus affects kidney function. Researchers tracked cases of acute kidney injury and looked for patterns to identify who is most at risk. The goal is to use this knowledge to impr…
Matched conditions: CORONA VIRUS INFECTION
Sponsor: University of Cologne • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC
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Can you safely get another COVID shot after a bad reaction? new study says yes
Knowledge-focused CompletedThis study looked at whether it is safe to give another dose of a COVID-19 mRNA vaccine to people who had a bad reaction to a previous dose, or to people with a history of allergies. It also included people with long COVID. A total of 137 adults took part. The goal was to see how…
Matched conditions: CORONA VIRUS INFECTION
Phase: PHASE4 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated May 11, 2026 20:48 UTC
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Lung cancer & COVID: new study tracks immune response in nearly 2,000 patients
Knowledge-focused CompletedThis study looked at nearly 2,000 adults with lung cancer who caught COVID-19. Researchers collected medical records and blood tests to understand how their immune systems responded. They also checked antibody levels 6 months after COVID vaccination. The goal was to learn more ab…
Matched conditions: CORONA VIRUS INFECTION
Sponsor: Fundación GECP • Aim: Knowledge-focused
Last updated May 11, 2026 20:37 UTC