New COVID-19 drug SIR1-365 tested for safety in hospitalized patients
NCT ID NCT04622332
First seen Nov 12, 2025 · Last updated May 16, 2026 · Updated 29 times
Summary
This early-stage trial tested the safety of an experimental drug called SIR1-365 in 45 hospitalized adults with severe COVID-19. Participants received either the drug or a placebo, and researchers monitored side effects and signs of inflammation. The goal was to see if the drug is safe enough for further testing, not to prove it cures the disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Aga Khan University Hospital
Karachi, Sindh, 74800, Pakistan
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Baptist Medical Center
Jackson, Mississippi, 39202, United States
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Dow University Hospital, Ojha Karachi
Karachi, Sindh, 74200, Pakistan
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Hospital Civil Fray Antonio Alcalde
Guadalajara, Jalisco, 14050, Mexico
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Hospital Universitario "Dr. José Eleuterio González"
Monterrey, Nuevo León, 64460, Mexico
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Media Sur - Medica Sur Tlalpan
Tlalpan, Mexico City, 14050, Mexico
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OSF St. Francis Medical Center
Peoria, Illinois, 61637, United States
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Sindh Infectious Disease Hospital
Karachi, Sindh, 74200, Pakistan
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Triple O Research Institute
West Palm Beach, Florida, 33407, United States
Conditions
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