CLOSTRIDIUM DIFFICILE INFECTION
Clinical trials for CLOSTRIDIUM DIFFICILE INFECTION explained in plain language.
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Should cancer patients get antibiotics for a dubious c. diff test? small trial seeks answers
Disease control CompletedThis study looked at whether giving the antibiotic vancomycin helps cancer patients who have diarrhea and a positive screening test for C. difficile but a negative toxin test. Only 9 patients were enrolled, far fewer than planned. Researchers measured changes in C. difficile leve…
Matched conditions: CLOSTRIDIUM DIFFICILE INFECTION
Phase: PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Dietary change may curb recurrent c. diff in cancer patients
Disease control CompletedThis study tested whether eating less fat and more fiber can reduce the chance of a repeat Clostridioides difficile infection in cancer patients. Eight participants with leukemia, lymphoma, or other cancers followed a specific diet. Researchers tracked diarrhea and measured C. di…
Matched conditions: CLOSTRIDIUM DIFFICILE INFECTION
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Poop pills? fecal transplants show promise for gut infections
Disease control CompletedThis study tested fecal microbiota transplant (FMT) in 24 adults with recurrent Clostridium difficile infection (C. diff) that didn't get better with standard antibiotics. FMT involves placing healthy donor stool into the patient's colon to restore good bacteria. The goal was to …
Matched conditions: CLOSTRIDIUM DIFFICILE INFECTION
Phase: PHASE4 • Sponsor: Methodist Health System • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Could a simple antibiotic taper stop c. diff relapse?
Prevention CompletedThis study tested whether extending standard vancomycin treatment for C. diff infection with a 2-week taper (lowering the dose gradually) reduces the chance of the infection returning. 263 adults who had a first episode or first recurrence of C. diff were randomly assigned to rec…
Matched conditions: CLOSTRIDIUM DIFFICILE INFECTION
Phase: PHASE3 • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Prevention
Last updated Jun 27, 2026 08:03 UTC
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Stool transplant plus antibody drug shows promise against recurrent c. diff in IBD patients
Prevention CompletedThis study tested whether combining a fecal microbiota transplant (FMT) with the drug bezlotoxumab could prevent repeat Clostridium difficile infections in people with inflammatory bowel disease (IBD). Sixty-one adults with at least two prior C. diff infections were randomly assi…
Matched conditions: CLOSTRIDIUM DIFFICILE INFECTION
Phase: PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Prevention
Last updated Jun 27, 2026 08:03 UTC