CLL / SLL
Clinical trials for CLL / SLL explained in plain language.
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Can a new drug combo outsmart resistant lymphomas?
Disease control Not yet recruitingThis phase II trial is testing whether a combination of two targeted drugs—pirtobrutinib and sonrotoclax—can shrink tumors in people with three types of B-cell lymphoma: transformed diffuse large B-cell lymphoma, relapsed or refractory chronic lymphocytic leukemia/small lymphocyt…
Matched conditions: CLL / SLL
Phase: PHASE2 • Sponsor: Changzhou No.2 People's Hospital • Aim: Disease control
Last updated Aug 08, 2026 00:03 UTC
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New pill shows promise for Hard-to-Treat lymphoma patients
Disease control Not yet recruitingThis Phase 2 trial tests lisaftoclax, an oral drug that blocks a protein helping cancer cells survive. It enrolls 75 adults with certain slow-growing lymphomas (CLL, WM, or MZL) who either cannot take standard BTK inhibitors due to health issues or have stopped them due to side e…
Matched conditions: CLL / SLL
Phase: PHASE2 • Sponsor: Henan Cancer Hospital • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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Two-Drug sequence aims to clear CLL cells and let patients stop treatment
Disease control Not yet recruitingThis phase 2 trial tests a treatment plan for people with newly diagnosed chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). Participants first take zanubrutinib alone for 12 cycles, then add sonrotoclax for another 12 cycles. The goal is to see if this seque…
Matched conditions: CLL / SLL
Phase: PHASE2 • Sponsor: Yi Shuhua • Aim: Disease control
Last updated Jul 04, 2026 00:00 UTC