CLINICALLY ISOLATED SYNDROME
Clinical trials for CLINICALLY ISOLATED SYNDROME explained in plain language.
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Can ocrelizumab tame MS inflammation from the start? new study aims to find out
Disease control OngoingThis study is testing whether the drug ocrelizumab (Ocrevus) can improve signs of inflammation in the spinal fluid of people newly diagnosed with relapsing multiple sclerosis (MS) or a high-risk first attack (clinically isolated syndrome). Thirty participants will receive ocreliz…
Matched conditions: CLINICALLY ISOLATED SYNDROME
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 08:15 UTC
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Lifestyle showdown: can diet and exercise replace MS drugs?
Disease control OngoingThis study looks at whether a healthy lifestyle—including diet, stress reduction, and exercise—can control symptoms and improve quality of life for people newly diagnosed with multiple sclerosis (MS) or its early stage, clinically isolated syndrome (CIS). Researchers are comparin…
Matched conditions: CLINICALLY ISOLATED SYNDROME
Phase: NA • Sponsor: Terry L. Wahls • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Massive italian MS registry aims to unlock secrets of the disease
Knowledge-focused ENROLLING_BY_INVITATIONThis observational study is creating a large database of up to 96,000 people with multiple sclerosis and related conditions in Italy. Researchers will collect information on patient demographics, treatments, and disease progression over time. The goal is to better understand thes…
Matched conditions: CLINICALLY ISOLATED SYNDROME
Sponsor: Fondazione Italiana Sclerosi Multipla • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Could a clogged brain drain trigger MS? new MRI study investigates
Knowledge-focused OngoingThis pilot study uses special MRI scans to check if the brain's waste-clearing system, called the glymphatic system, is not working properly in people with Clinically Isolated Syndrome (CIS), which is often the first sign of Multiple Sclerosis (MS). Researchers will compare scans…
Matched conditions: CLINICALLY ISOLATED SYNDROME
Sponsor: University of Exeter • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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AI brain scans could revolutionize MS care
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether using an AI tool to analyze brain MRIs helps doctors spot signs of multiple sclerosis (MS) activity more accurately. About 750 people with MS or early warning signs will be split into two groups: one where doctors use the AI tool, and one where they re…
Matched conditions: CLINICALLY ISOLATED SYNDROME
Phase: NA • Sponsor: icometrix • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC