CLINICALLY ISOLATED SYNDROME
Clinical trials for CLINICALLY ISOLATED SYNDROME explained in plain language.
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MS study: could lifestyle changes replace drugs?
Disease control OngoingThis study looks at whether a healthy lifestyle—including diet, stress reduction, and exercise—can control symptoms and improve quality of life for people newly diagnosed with multiple sclerosis (MS) or its early stage, clinically isolated syndrome. Researchers are comparing two …
Matched conditions: CLINICALLY ISOLATED SYNDROME
Phase: NA • Sponsor: Terry L. Wahls • Aim: Disease control
Last updated May 11, 2026 20:53 UTC
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New MS drug shows promise in calming brain inflammation early
Knowledge-focused OngoingThis study looks at how ocrelizumab, a multiple sclerosis (MS) drug, changes certain markers in the spinal fluid of people newly diagnosed with relapsing MS or a high-risk first episode. Researchers want to see if early treatment can reduce signs of chronic inflammation in the br…
Matched conditions: CLINICALLY ISOLATED SYNDROME
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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AI brain scans could spot hidden MS activity
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests whether an AI tool (icobrain mr) that analyzes brain MRI scans can help doctors spot signs of active multiple sclerosis (MS) more accurately than standard scans alone. About 750 adults with MS or early warning signs (RIS/CIS) will be split into two groups: one wh…
Matched conditions: CLINICALLY ISOLATED SYNDROME
Phase: NA • Sponsor: icometrix • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Brain's Waste-Cleaning system may hold key to early MS detection
Knowledge-focused OngoingThis study looks at whether the brain's natural waste-cleaning system, called the glymphatic system, works differently in people with Clinically Isolated Syndrome (CIS), which can be an early sign of multiple sclerosis (MS). Researchers will use special MRI scans to compare 30 ad…
Matched conditions: CLINICALLY ISOLATED SYNDROME
Sponsor: University of Exeter • Aim: Knowledge-focused
Last updated May 11, 2026 20:37 UTC