CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Clinical trials for CLINICAL STAGE IV GASTRIC CANCER AJCC V8 explained in plain language.
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New drug combo targets Hard-to-Treat HER2 cancers
Disease control OngoingThis early-stage study tests a combination of two drugs—trastuzumab deruxtecan (DS-8201a) and ceralasertib—in people with advanced solid tumors that have a HER2 mutation. The first part finds the safest dose and checks side effects. The second part compares the combo to DS-8201a …
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 16, 2026 12:49 UTC
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New drug combo targets Hard-to-Treat cancers
Disease control OngoingThis early-stage trial tests a new drug (BAY 1895344) combined with standard chemotherapy for people with advanced solid tumors, especially bladder cancer. The goal is to find the safest dose and see how well the combination works. About 74 adults with cancers like lung, ovarian,…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 15, 2026 19:04 UTC
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New way to deliver chemo shows promise for stomach cancer patients
Disease control OngoingThis early-phase study tests a chemotherapy drug called paclitaxel, given directly into the abdomen, for people with advanced stomach cancer that has spread to the lining of the belly. The main goal is to find the safest dose and understand side effects. About 27 adults with this…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 15, 2026 19:03 UTC
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New combo therapy targets Hard-to-Treat cancers
Disease control OngoingThis early-phase trial tests the safety and best dose of sonidegib combined with pembrolizumab in 36 adults with advanced solid tumors (cancers that have spread). Sonidegib blocks enzymes that help tumors grow, while pembrolizumab boosts the immune system to attack cancer. The go…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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Stomach cancer combo fails to shrink tumors in early trial
Disease control OngoingThis study tested a combination of two drugs, berzosertib and irinotecan, in 17 people with advanced stomach or gastroesophageal junction cancer that had a specific genetic change (TP53 mutation) and was no longer responding to other treatments. The goal was to see if the combina…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 10, 2026 13:27 UTC
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Radiation boosts chemo for Limited-Stage esophageal and stomach cancer?
Disease control OngoingThis study tests whether adding radiation therapy to standard chemotherapy helps people with esophageal or stomach cancer that has spread to a few other spots in the body (oligometastatic). About 314 participants will receive either chemo alone or chemo plus radiation. The goal i…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: PHASE3 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated Jun 08, 2026 13:17 UTC
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Home monitoring may keep cancer patients out of the ER
Symptom relief OngoingThis study tests whether using telemedicine and remote monitoring can help people with advanced digestive cancers manage chemotherapy side effects at home, reducing the need for emergency room visits and hospital stays. About 750 patients and their caregivers will receive enhance…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 16, 2026 23:08 UTC
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Massive biobank aims to unlock Cancer's secrets
Knowledge-focused OngoingThis study collects tissue and blood samples, along with medical information, from 1,600 people with various advanced cancers. Researchers will track these samples over time to learn how cancer changes and why some treatments stop working. The goal is to build a resource for futu…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:55 UTC