CLINICAL STAGE IV CUTANEOUS MELANOMA AJCC V8
Clinical trials for CLINICAL STAGE IV CUTANEOUS MELANOMA AJCC V8 explained in plain language.
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Doctors test engineered virus to attack deadly skin cancer
Disease control TerminatedThis early-phase study tested a genetically modified virus designed to kill melanoma cancer cells. The virus was injected directly into tumors and given intravenously to patients with advanced melanoma that had stopped responding to standard treatments. The main goals were to fin…
Matched conditions: CLINICAL STAGE IV CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Two-Pronged attack tested against brain tumors
Disease control TerminatedThis early-phase study tested a combination of two drugs, bintrafusp alfa and pimasertib, for patients with cancer that had spread to the brain (brain metastases). The goal was to find a safe dose and see if the combination could help control the brain tumors and help patients li…
Matched conditions: CLINICAL STAGE IV CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Can a malaria drug help beat tough skin cancer?
Disease control TerminatedThis study tested whether adding the drug hydroxychloroquine to a standard two-drug treatment (dabrafenib and trametinib) could better control advanced melanoma that has a specific BRAF gene mutation. It aimed to see if the three-drug combo could delay cancer growth longer than t…
Matched conditions: CLINICAL STAGE IV CUTANEOUS MELANOMA AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC