CLINICAL STAGE III GASTRIC CANCER AJCC V8
Clinical trials for CLINICAL STAGE III GASTRIC CANCER AJCC V8 explained in plain language.
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New drug combo targets Hard-to-Treat HER2 cancers
Disease control OngoingThis early-stage study tests a combination of two drugs—trastuzumab deruxtecan (DS-8201a) and ceralasertib—in people with advanced solid tumors that have a HER2 mutation. The first part finds the safest dose and checks side effects. The second part compares the combo to DS-8201a …
Matched conditions: CLINICAL STAGE III GASTRIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 16, 2026 12:49 UTC
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New drug combo targets Hard-to-Treat cancers
Disease control OngoingThis early-stage trial tests a new drug (BAY 1895344) combined with standard chemotherapy for people with advanced solid tumors, especially bladder cancer. The goal is to find the safest dose and see how well the combination works. About 74 adults with cancers like lung, ovarian,…
Matched conditions: CLINICAL STAGE III GASTRIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 15, 2026 19:04 UTC
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New combo therapy targets Hard-to-Treat cancers
Disease control OngoingThis early-phase trial tests the safety and best dose of sonidegib combined with pembrolizumab in 36 adults with advanced solid tumors (cancers that have spread). Sonidegib blocks enzymes that help tumors grow, while pembrolizumab boosts the immune system to attack cancer. The go…
Matched conditions: CLINICAL STAGE III GASTRIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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Shorter radiation before stomach cancer surgery shows promise in early trial
Disease control OngoingThis early-phase trial tests whether a shorter course of chemoradiation (2 weeks instead of 5) followed by standard chemotherapy is safe and effective for people with stomach cancer who will have surgery. About 25 participants will receive the shorter radiation along with chemo d…
Matched conditions: CLINICAL STAGE III GASTRIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 11, 2026 12:10 UTC
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Immunotherapy combo shows promise for genetic stomach cancer subtype
Disease control OngoingThis study looks at whether an immunotherapy drug (atezolizumab) alone or combined with chemotherapy can help control a certain type of stomach or gastroesophageal junction cancer that has a genetic feature called MSI-H/dMMR. About 240 adults with localized or locoregional cancer…
Matched conditions: CLINICAL STAGE III GASTRIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 10, 2026 13:27 UTC
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Stomach cancer combo fails to shrink tumors in early trial
Disease control OngoingThis study tested a combination of two drugs, berzosertib and irinotecan, in 17 people with advanced stomach or gastroesophageal junction cancer that had a specific genetic change (TP53 mutation) and was no longer responding to other treatments. The goal was to see if the combina…
Matched conditions: CLINICAL STAGE III GASTRIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 10, 2026 13:27 UTC
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Hot chemo wash during surgery may stop stomach Cancer's return
Prevention ENROLLING_BY_INVITATIONThis study tests whether giving heated chemotherapy directly into the abdomen during surgery can prevent stomach or gastroesophageal junction cancer from returning in the belly lining. It is for patients at high risk of recurrence. The approach aims to kill any stray cancer cells…
Matched conditions: CLINICAL STAGE III GASTRIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Prevention
Last updated Jun 10, 2026 13:28 UTC
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New recovery protocol aims to get stomach cancer patients home sooner
Symptom relief OngoingThis study tests a special recovery plan for people with stomach cancer who are having surgery. The plan focuses on reducing pain and nausea, helping the bowels work sooner, and shortening hospital stays. About 52 participants with early to advanced stomach cancer will take part …
Matched conditions: CLINICAL STAGE III GASTRIC CANCER AJCC V8
Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated Jun 16, 2026 12:49 UTC