CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8
Clinical trials for CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8 explained in plain language.
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Tiny particles supercharge radiation to fight esophageal cancer
Disease control Recruiting nowThis early-stage study is testing a new nanoparticle treatment called NBTXR3 for people with esophageal cancer. The nanoparticles are injected directly into the tumor and are designed to make radiation therapy more effective at killing cancer cells when combined with standard che…
Matched conditions: CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 01, 2026 18:41 UTC
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Proton vs. photon: race to find safer radiation for esophageal cancer
Disease control Recruiting nowThis study aims to find out if proton beam radiation therapy works better and causes fewer serious heart and lung side effects than the standard photon radiation therapy for people with esophageal cancer. About 300 patients with stage I-IVA esophageal cancer will be randomly assi…
Matched conditions: CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Shorter, stronger radiation blitz aims to wipe out tumors before surgery
Disease control Recruiting nowThis study is testing a new pre-surgery treatment plan for early to mid-stage esophageal cancer. It combines a shorter, more intense 3-week radiation schedule with a specific chemotherapy regimen (FOLFOX) to try to kill more cancer cells and potentially have fewer side effects. T…
Matched conditions: CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Major cancer trial tests if adding one drug helps patients live longer
Disease control Recruiting nowThis large, late-stage trial is testing which of two chemotherapy combinations works better for people with advanced stomach or esophageal cancer that has spread and cannot be removed by surgery. About 382 participants will be randomly assigned to receive either the standard two-…
Matched conditions: CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New hope for Tough-to-Treat cancers: adding immune booster to standard care
Disease control Recruiting nowThis study is for people with advanced stomach or esophageal cancer that has worsened after initial treatment. It tests if adding an immunotherapy drug called nivolumab to the standard two-drug chemotherapy helps control the cancer better and helps patients live longer. About 224…
Matched conditions: CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Stress-Blocking pill joins fight against tough stomach cancers
Disease control Recruiting nowThis study is testing if adding propranolol, a common blood pressure and anxiety medication, makes standard chemotherapy and immunotherapy more effective for people with advanced cancer where the esophagus meets the stomach. The idea is that stress hormones might weaken the immun…
Matched conditions: CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Can a simple ear tap fight cancer weight loss?
Symptom relief Recruiting nowThis study is testing if a simple, non-invasive therapy called ear acupressure can help improve appetite and prevent weight loss in people with certain advanced cancers. Researchers will recruit 66 patients with stomach, esophageal, or pancreatic cancer to see if applying small a…
Matched conditions: CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: NA • Sponsor: University of Washington • Aim: Symptom relief
Last updated Mar 12, 2026 13:52 UTC