CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8
Clinical trials for CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8 explained in plain language.
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Could a common heart drug boost cancer treatment?
Disease control Recruiting nowThis study tests whether adding propranolol (a beta-blocker used for heart conditions) to standard chemotherapy and immunotherapy can help people with advanced esophageal or stomach cancer that cannot be surgically removed. The drug may reduce stress hormones that can weaken the …
Matched conditions: CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated May 17, 2026 04:44 UTC
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Radiation-Activated nanoparticle targets esophageal tumors in early trial
Disease control Recruiting nowThis early-phase study tests a new drug called NBTXR3, which is injected into the tumor and activated by radiation therapy to destroy cancer cells. It is given alongside standard chemotherapy for people with esophageal adenocarcinoma. The main goals are to find the safest dose an…
Matched conditions: CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 17, 2026 04:43 UTC
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New combo shows promise for tough stomach cancers
Disease control Recruiting nowThis study tests whether adding the immunotherapy drug nivolumab to standard chemotherapy (paclitaxel and ramucirumab) helps people with advanced stomach or esophageal cancer live longer without their disease getting worse. About 224 adults whose cancer has a specific marker (PD-…
Matched conditions: CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New radiation method could spare heart and lungs in esophageal cancer patients
Disease control Recruiting nowThis study compares two radiation techniques for people with stage I to IVA esophageal cancer: proton beam therapy (PBT) and intensity modulated photon radiotherapy (IMRT). The goal is to see which one helps patients live longer and causes fewer serious heart and lung side effect…
Matched conditions: CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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New combo aims to boost esophageal cancer treatment before surgery
Disease control Recruiting nowThis study is for people with stage I to III esophageal or gastroesophageal junction cancer. It tests a shorter, higher-dose radiation schedule given with chemotherapy (FOLFOX) before surgery. The goal is to see if this approach can destroy more tumor cells and improve outcomes. …
Matched conditions: CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 11, 2026 20:47 UTC
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New chemo cocktail aims to extend life in hard-to-treat stomach cancers
Disease control Recruiting nowThis study compares two chemotherapy combinations for people with advanced stomach, esophageal, or gastroesophageal junction cancer that cannot be removed by surgery. About 382 participants will receive either the standard FOLFOX chemo (with or without the immunotherapy nivolumab…
Matched conditions: CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 04, 2026 16:18 UTC
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Ear acupressure: a new hope for cancer appetite loss?
Symptom relief Recruiting nowThis study tests whether a simple, non-invasive technique called auricular acupressure (using small pellets on the ear) can help improve appetite and prevent weight loss in people with advanced stomach, esophageal, or pancreatic cancer. About 66 participants will receive either a…
Matched conditions: CLINICAL STAGE III ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: NA • Sponsor: University of Washington • Aim: Symptom relief
Last updated May 17, 2026 04:49 UTC