Choroidal melanoma
Clinical trials for Choroidal melanoma explained in plain language.
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New eye injection could spare sight in melanoma patients
Disease control OngoingThis Phase 3 trial tests a new drug called belzupacap sarotalocan (AU-011) for people with small choroidal melanoma or suspicious spots in the eye. The drug is injected into the eye and activated by a laser to target cancer cells. The study compares it to a sham (fake) procedure …
Matched conditions: CHOROIDAL MELANOMA
Phase 3 • Sponsor: Aura Biosciences • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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New combo therapy aims to shrink eye tumors before radiation
Disease control By invitation onlyThis early-phase trial tests whether injecting the chemotherapy drug melphalan directly into the eye's blood vessels can shrink large uveal melanomas (eye cancers) enough to then treat them with radiation. Ten adults with tumors at least 8 mm thick will receive the chemo injectio…
Matched conditions: CHOROIDAL MELANOMA
Phase 1/2 • Sponsor: Hospital das Clínicas de Ribeirão Preto • Aim: Disease control
Last updated Jun 26, 2026 17:03 UTC
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Researchers track Long-Term safety of experimental eye cancer treatment
Knowledge-focused By invitation onlyThis study is a long-term follow-up for 100 people who completed a previous trial of bel-sar, an experimental treatment for early choroidal melanoma (a type of eye cancer). Participants will not receive any new treatment but will be monitored for about 5 more years to check for s…
Matched conditions: CHOROIDAL MELANOMA
Sponsor: Aura Biosciences • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
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Researchers track Long-Term safety of experimental eye cancer drug
Knowledge-focused OngoingThis registry follows 63 patients with choroidal melanoma or early eye lesions who were treated with the experimental drug bel-sar in earlier studies. The goal is to monitor long-term safety, side effects, and any spread of the disease over time. Participants are not receiving ne…
Matched conditions: CHOROIDAL MELANOMA
Sponsor: Aura Biosciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC