CHEMORADIOTHERAPY

This phase 2 trial is testing whether adding the drug QL1706 to standard chemotherapy and radiation can help people with limited-stage small cell lung cancer. QL1706 is a type of immunotherapy that targets two immune checkpoints to help the body fight cancer. The study will enrol…

This study tests whether a combination of chemotherapy and radiation (total neoadjuvant therapy, or TNT) can shrink rectal tumors enough so that some patients can avoid surgery and instead be monitored closely. About 400 adults with early-stage rectal cancer will be randomly assi…

This phase 3 trial tests whether adding two drugs—toripalimab and capecitabine—after standard chemoradiation can prevent esophageal cancer from coming back. About 242 adults with advanced esophageal cancer who finished chemoradiation without progression will be enrolled. The goal…

This phase II trial tests whether adding two drugs—toripalimab (an immunotherapy) and surufatinib (a targeted therapy)—to standard chemoradiation can help people with limited-stage small cell lung cancer live longer without the disease getting worse. About 47 adults aged 18–75 wi…

This study tests whether a drug called mecapegfilgrastim can safely prevent moderate-to-severe myelosuppression (low blood cell counts) caused by chemotherapy and radiation for lung or esophageal cancer. About 30 adults aged 18-75 will receive the drug alongside their standard ca…

This phase II trial tests whether adding the drug surufatinib to standard chemo-immunotherapy and radiation can help people with advanced esophageal cancer that cannot be removed by surgery. The study will enroll 69 participants in China and track how long they live without the c…

This study is for people with locally advanced rectal cancer that hasn't spread. It tests whether adding an immunotherapy drug (PD-1 inhibitor) to a standard treatment plan (short-course radiation plus chemotherapy and targeted therapy) can lead to a complete disappearance of the…

This study follows 1,538 cancer patients in China to see how their nutritional status affects how well they handle chemotherapy and radiation, their quality of life, and how long they live. Researchers will track changes in diet, weight, and blood markers over time. The goal is t…

This study looks at whether hospitals in India are following standard guidelines for treating cervical cancer with radiation and chemotherapy. Researchers will review records from over 600 patients treated at multiple centers to see how often the recommended care is given. The go…