CATAPLEXY
Clinical trials for CATAPLEXY explained in plain language.
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New pill aims to stop Narcolepsy's sudden muscle weakness
Symptom relief CompletedThis study tested an experimental drug called AXS-12 (reboxetine) in 90 people with narcolepsy who experience cataplexy (sudden muscle weakness) and excessive daytime sleepiness. Participants took either the drug or a placebo twice daily for several weeks. The main goal was to se…
Matched conditions: CATAPLEXY
Phase: PHASE3 • Sponsor: Axsome Therapeutics, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:38 UTC
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New drug shows promise for reducing narcolepsy attacks over the long term
Symptom relief CompletedThis study looked at the long-term safety and effectiveness of a drug called AXS-12 for people with narcolepsy who also have sudden muscle weakness (cataplexy) and severe daytime sleepiness. 68 people who had already completed an earlier study took AXS-12 and were monitored for s…
Matched conditions: CATAPLEXY
Phase: PHASE3 • Sponsor: Axsome Therapeutics, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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New Once-Nightly pill could simplify narcolepsy treatment
Symptom relief CompletedThis study tested a new once-nightly medication called FT218 for people with narcolepsy who experience excessive daytime sleepiness and sudden muscle weakness (cataplexy). It included 184 participants, some already on a twice-nightly medication and some new to treatment. The goal…
Matched conditions: CATAPLEXY
Phase: PHASE3 • Sponsor: Avadel • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC