CASTLEMAN DISEASE
Clinical trials for CASTLEMAN DISEASE explained in plain language.
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Early trial tests new drug mixes for Tough-to-Treat cancers
Disease control OngoingThis early-stage trial aims to find safe doses and understand side effects of several drug combinations for patients with advanced cancers that haven't responded to standard treatments. The study involves 155 participants with various advanced or metastatic cancers and some rare …
Matched conditions: CASTLEMAN DISEASE
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New hope for rare immune disorder patients who failed standard therapy
Disease control OngoingThis study is testing a drug called sirolimus for adults with a rare immune system disorder called idiopathic multicentric Castleman disease (iMCD) who have not gotten better with standard treatments. Participants will take sirolimus daily for a year to see if it reduces symptoms…
Matched conditions: CASTLEMAN DISEASE
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Mar 18, 2026 14:40 UTC