CASTLEMAN DISEASE
Clinical trials for CASTLEMAN DISEASE explained in plain language.
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New drug cocktail trial aims to tame tough tumors
Disease control OngoingThis early-phase trial tests the safety and best doses of two drugs (bevacizumab and temsirolimus) given alone or with other medicines (valproic acid or cetuximab) in people with advanced cancer or certain non-cancerous diseases that are hard to treat. The goal is to find the hig…
Matched conditions: CASTLEMAN DISEASE
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Old drug, new hope: sirolimus shows promise for rare castleman disease
Disease control OngoingThis study tested the drug sirolimus in 7 people with idiopathic multicentric Castleman disease (iMCD), a rare condition where the immune system causes swollen lymph nodes and severe symptoms. Participants had already tried other treatments without success. The goal was to see if…
Matched conditions: CASTLEMAN DISEASE
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated May 04, 2026 16:20 UTC