CANCER OF HEAD AND NECK
Clinical trials for CANCER OF HEAD AND NECK explained in plain language.
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Immunotherapy combo shows promise in reducing head and neck cancer recurrence
Disease control CompletedThis phase 2 trial tested whether adding the immunotherapy drug pembrolizumab (Keytruda) to standard surgery, radiation, and chemotherapy could help prevent head and neck cancer from coming back. The study enrolled 67 adults with advanced, surgically removable head and neck squam…
Matched conditions: CANCER OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Can less radiation be safer without sacrificing cancer control?
Disease control CompletedThis study tested whether giving lower doses of radiation after surgery for head and neck cancer could reduce long-term side effects like dry mouth and trouble swallowing, while still keeping the cancer from coming back. About 200 patients with certain stages of oral, throat, or …
Matched conditions: CANCER OF HEAD AND NECK
Phase: PHASE2 • Sponsor: University of Erlangen-Nürnberg Medical School • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Cialis and keytruda together against head and neck cancer: small trial shows promise?
Disease control CompletedThis completed phase II study tested a combination of two drugs—tadalafil (Cialis) and pembrolizumab (Keytruda)—in 7 adults with advanced head and neck cancer that had spread or come back. The goal was to see if the combination was safe and could help control the disease. Because…
Matched conditions: CANCER OF HEAD AND NECK
Phase: PHASE2 • Sponsor: University of California, San Diego • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New chemo cocktail aims to tame aggressive head and neck tumors with fewer side effects
Disease control CompletedThis phase II trial tested a combination of three chemotherapy drugs (cisplatin, 5-fluorouracil, and docetaxel) at adapted doses in 105 patients with locally advanced head and neck cancer that could not be surgically removed. The goal was to see if this adjusted dosing could effe…
Matched conditions: CANCER OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Groupe Oncologie Radiotherapie Tete et Cou • Aim: Disease control
Last updated Jun 26, 2026 13:19 UTC
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Sound waves zapped brain to kill cancer pain – tiny study shows promise
Symptom relief CompletedThis pilot study tested a device that uses focused ultrasound to create a small lesion in the brain's pain pathway, aiming to relieve severe, opioid-resistant pain from head and neck cancer. Six participants underwent the procedure and were followed for 6 months to check safety a…
Matched conditions: CANCER OF HEAD AND NECK
Phase: NA • Sponsor: Jeff Elias, MD • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Mindfulness meditation boosts hope and quality of life in head and neck cancer patients
Symptom relief CompletedThis study tested whether a mindfulness-based stress reduction (MBSR) program could improve quality of life and positive feelings like hope and optimism in people newly diagnosed with head and neck cancer. 110 participants were split into two groups: one received MBSR training, t…
Matched conditions: CANCER OF HEAD AND NECK
Phase: NA • Sponsor: Universiti Sains Malaysia • Aim: Symptom relief
Last updated Jun 26, 2026 15:55 UTC
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New imaging technique could help doctors predict cancer treatment response
Knowledge-focused CompletedThis study tested whether a PET scan using a tracer called FMISO can measure oxygen levels (hypoxia) in head and neck cancers. Sixteen patients received the scan before starting radiotherapy. The goal was to see if the amount of hypoxia seen on the scan could predict how well the…
Matched conditions: CANCER OF HEAD AND NECK
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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New study reveals how cancer treatment affects swelling and quality of life
Knowledge-focused CompletedThis study looked at 50 people with head and neck cancer to see how often swelling (lymphedema) happens after treatment. Researchers measured fluid levels in the head and neck before and after cancer therapy and checked quality of life. The goal was to better understand the probl…
Matched conditions: CANCER OF HEAD AND NECK
Sponsor: Lund University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC