CANCER OF HEAD AND NECK
Clinical trials for CANCER OF HEAD AND NECK explained in plain language.
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New chemo cocktail shows promise for tough head and neck cancers
Disease control CompletedThis study tested a combination of three chemotherapy drugs (cisplatin, 5-fluorouracil, and docetaxel) at adjusted doses in 105 patients with advanced head and neck cancer that could not be surgically removed. The goal was to see how well the treatment worked at shrinking tumors …
Matched conditions: CANCER OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Groupe Oncologie Radiotherapie Tete et Cou • Aim: Disease control
Last updated May 17, 2026 07:04 UTC
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New drug combo shows promise for tough head and neck cancers
Disease control CompletedThis study tested whether adding tadalafil (a drug for erectile dysfunction) to pembrolizumab (an immunotherapy) could help people with advanced head and neck cancer that has spread or come back. Seven adults with this cancer took part. The goal was to see if the combination was …
Matched conditions: CANCER OF HEAD AND NECK
Phase: PHASE2 • Sponsor: University of California, San Diego • Aim: Disease control
Last updated May 17, 2026 06:47 UTC
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Immunotherapy shows promise in shrinking head and neck tumors before surgery
Disease control CompletedThis study tested whether giving the immunotherapy drug pembrolizumab (MK-3475) before standard surgery could help prevent head and neck cancer from coming back. It included 67 adults with advanced, surgically removable head and neck cancer. The main goal was to see if the drug c…
Matched conditions: CANCER OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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Less radiation, same cancer control? new study offers hope for head and neck patients
Disease control CompletedThis study tested whether a lower dose of radiation after surgery could reduce long-term side effects like dry mouth and swallowing problems in head and neck cancer patients. 200 adults with certain stages of oral, throat, or voice box cancer took part. The goal was to see if the…
Matched conditions: CANCER OF HEAD AND NECK
Phase: PHASE2 • Sponsor: University of Erlangen-Nürnberg Medical School • Aim: Disease control
Last updated May 12, 2026 13:39 UTC
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Mindfulness boosts hope and quality of life in head and neck cancer patients
Symptom relief CompletedThis study looked at whether a mindfulness program (MBSR) can improve quality of life and positive feelings like hope and growth in people newly diagnosed with head and neck cancer. 110 adults who had finished surgery and were getting other treatments took part. The goal was to s…
Matched conditions: CANCER OF HEAD AND NECK
Phase: NA • Sponsor: Universiti Sains Malaysia • Aim: Symptom relief
Last updated May 17, 2026 06:50 UTC
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Sound waves zap cancer pain: new hope for sufferers
Symptom relief CompletedThis small pilot study tested a new way to treat severe, opioid-resistant pain in people with head and neck cancer. Doctors used focused ultrasound to create a tiny lesion in the brain's pain pathway, aiming to reduce pain without surgery or drugs. Six participants were followed …
Matched conditions: CANCER OF HEAD AND NECK
Phase: NA • Sponsor: Jeff Elias, MD • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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Oxygen-Sensing scan may predict cancer treatment success
Knowledge-focused CompletedThis study looked at whether a special PET scan called FMISO can measure oxygen levels in head and neck tumors. Sixteen adults with head and neck cancer received the scan before starting radiation therapy. Researchers then checked if the scan results matched how well the cancer r…
Matched conditions: CANCER OF HEAD AND NECK
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated May 17, 2026 06:52 UTC
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New study reveals how cancer treatment affects swelling in the head and neck
Knowledge-focused CompletedThis study looked at 50 people treated for head and neck cancer to see how often swelling (lymphedema) happens and how it affects quality of life. Researchers measured fluid levels in the head and neck before and after cancer treatment. The goal was to learn more about this side …
Matched conditions: CANCER OF HEAD AND NECK
Sponsor: Lund University • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC