BRCA MUTATION
Clinical trials for BRCA MUTATION explained in plain language.
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New drug targets Hard-to-Treat cancers in early trial
Disease control Recruiting nowThis study is testing an experimental drug called ETX-19477 in people with advanced solid tumors (cancers that have spread or can't be removed). The goal is to find a safe dose and see if it can shrink tumors. About 120 adults with cancers like breast, ovarian, prostate, or other…
Matched conditions: BRCA MUTATION
Phase: PHASE1, PHASE2 • Sponsor: 858 Therapeutics, Inc. • Aim: Disease control
Last updated Jun 17, 2026 04:27 UTC
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New drug combo targets tough cancers in early trial
Disease control Recruiting nowThis early-phase study tests a combination of two oral drugs, olaparib and ASTX727, in adults with advanced solid tumors that have mutations in genes like BRCA1, BRCA2, PALB2, ATM, or CHEK2. The main goals are to find the safest dose and to check for side effects. About 18 partic…
Matched conditions: BRCA MUTATION
Phase: PHASE1 • Sponsor: Varun Monga, MBBS • Aim: Disease control
Last updated Jun 10, 2026 13:27 UTC
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New scan may improve cancer detection for men with inherited risk
Diagnosis Recruiting nowThis study compares a new PET-CT scan (FCH-PET-CT) to standard imaging (bone scan and MRI/CT) to see which better finds cancer that has spread outside the pelvis in men with prostate cancer and specific DNA repair gene mutations. About 50 men with these mutations will be enrolled…
Matched conditions: BRCA MUTATION
Sponsor: Institute of Cancer Research, United Kingdom • Aim: Diagnosis
Last updated Jun 17, 2026 04:29 UTC
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Ultrasound AI may spot hidden cancer genes in healthy ovaries
Diagnosis Recruiting nowThis study aims to see if a computer model can predict BRCA1/2 gene mutations by analyzing ultrasound images of healthy ovaries. Over 6,000 women will provide images and genetic test results to train and test the model. If successful, this could become a simple, non-invasive scre…
Matched conditions: BRCA MUTATION
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Diagnosis
Last updated Jun 01, 2026 18:04 UTC