BRCA MUTATION
Clinical trials for BRCA MUTATION explained in plain language.
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New pill could keep ovarian cancer at bay for women with BRCA mutation
Disease control OngoingThis study tests whether a daily pill called olaparib can help keep advanced ovarian cancer from coming back in women with a BRCA gene mutation. About 450 women who finished initial chemotherapy and had a good response will receive either olaparib or a placebo. The goal is to see…
Matched conditions: BRCA MUTATION
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 15, 2026 19:02 UTC
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Gene-Targeted prostate screening study aims to save High-Risk men
Knowledge-focused OngoingThis study looks at whether yearly PSA tests can find prostate cancer early in men who have inherited certain gene mutations (BRCA1, BRCA2, or mismatch repair genes) that raise their risk. About 3,500 men aged 40-69, both with and without these mutations, will be screened and com…
Matched conditions: BRCA MUTATION
Sponsor: Institute of Cancer Research, United Kingdom • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:50 UTC
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New database aims to outsmart pancreatic cancer
Knowledge-focused OngoingThis study is creating a large database of people at high risk for pancreatic cancer, including those with cysts, genetic conditions, or other risk factors. The goal is to track their health over time to find better ways to detect the disease early or even prevent it. About 317 p…
Matched conditions: BRCA MUTATION
Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:05 UTC
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New study explores how genetic risk scores shape ovarian cancer decisions
Knowledge-focused OngoingThis study interviews 24 women aged 25 and older who have a BRCA1 or BRCA2 mutation to learn how they might use polygenic risk scores and multi-cancer early detection tests when deciding about cancer screening or risk-reducing surgery. The goal is to better understand women's att…
Matched conditions: BRCA MUTATION
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:29 UTC