BIOEQUIVALANCE
Clinical trials for BIOEQUIVALANCE explained in plain language.
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Will a cheaper diabetes pill match the original?
Knowledge-focused CompletedThis trial checks whether a generic extended-release tablet containing sitagliptin and metformin works the same as the brand-name Janumet XR. Healthy adults aged 18 to 55 take a single dose of each version on separate occasions, and researchers compare how much of the drugs reach…
Matched conditions: BIOEQUIVALANCE
Phase: NA • Sponsor: ADIUM • Aim: Knowledge-focused
Last updated Aug 16, 2026 00:00 UTC
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Will a cheaper diabetes pill match the original?
Knowledge-focused CompletedThis trial asks whether a generic extended-release tablet containing sitagliptin and metformin works the same as the brand-name version (Janumet XR) in healthy adults. Each participant takes a single dose of both medications at different times, and blood tests compare how the bod…
Matched conditions: BIOEQUIVALANCE
Phase: NA • Sponsor: ADIUM • Aim: Knowledge-focused
Last updated Aug 16, 2026 00:00 UTC
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Will a cheaper diabetes pill match the original?
Knowledge-focused CompletedThis trial asks whether a generic extended-release tablet combining sitagliptin and metformin works the same as the brand-name Janumet XR. Healthy adults aged 18 to 55 will receive a single dose of each version in random order, and researchers will compare how much of the drug re…
Matched conditions: BIOEQUIVALANCE
Phase: NA • Sponsor: ADIUM • Aim: Knowledge-focused
Last updated Aug 16, 2026 00:00 UTC
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Generic tamsulosin put to the test: will it match the brand?
Knowledge-focused CompletedThis trial investigates whether a test version of tamsulosin 0.4 mg prolonged-release tablets works the same as the reference product (Omnic Ocas) in healthy male volunteers. Thirty-four men aged 18 to 55 will receive single doses of each tablet under fasted conditions in a cross…
Matched conditions: BIOEQUIVALANCE
Phase: NA • Sponsor: ADIUM • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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Healthy volunteers test generic vs. brand drug equivalence
Knowledge-focused CompletedThis study checked if two different oral versions of vortioxetine 20 mg tablets are absorbed the same way in the body. Twenty healthy adults aged 18 to 55 took a single dose of each version in a random order. The goal was to measure drug levels in the blood, not to treat any cond…
Matched conditions: BIOEQUIVALANCE
Phase: PHASE1 • Sponsor: ADIUM • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Progesterone showdown: are two injections equally effective?
Knowledge-focused CompletedThis study tested whether a new injectable progesterone (Prontogest) works the same in the body as the standard progesterone injection. Twenty-six healthy postmenopausal women received single doses of each in a randomized order. The goal was to check if the two formulations are b…
Matched conditions: BIOEQUIVALANCE
Phase: PHASE1 • Sponsor: Zi Diligence Biocenter • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Generic diabetes pill matches brand in healthy volunteer test
Knowledge-focused CompletedThis study tested whether a generic version of empagliflozin (25 mg) works the same as the brand-name drug Jardiance® in 32 healthy adults. Participants took a single dose of each tablet under fasting conditions, and researchers measured drug levels in the blood to check for bioe…
Matched conditions: BIOEQUIVALANCE
Phase: NA • Sponsor: ADIUM • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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New trazodone formula tested for similarity to current version
Knowledge-focused CompletedThis study tested whether a new polymer version of the antidepressant trazodone (150 mg and 300 mg tablets) is absorbed in the body the same way as the current Contramid® version. Sixty-four healthy adults took both forms in a crossover design to measure drug levels in the blood.…
Matched conditions: BIOEQUIVALANCE
Phase: PHASE1 • Sponsor: Aziende Chimiche Riunite Angelini Francesco S.p.A • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:07 UTC