BINGE-EATING DISORDER

This study tests whether tirzepatide, a drug used for diabetes and weight loss, can help adults with obesity and binge-eating disorder. About 105 participants will receive tirzepatide, a placebo, or another drug (lisdexamfetamine), plus guided self-help therapy. The main goals ar…

This study tests an investigational medication called solriamfetol to see if it can reduce binge eating episodes in adults with binge eating disorder. About 450 participants will receive either the drug or a placebo for 12 weeks. The main goal is to measure the change in the numb…

This study looks at whether adding a GLP-1 appetite suppressant to behavioral therapy helps people with severe obesity and binge eating disorder. About 80 adults will be split into two groups: one gets the drug plus therapy, the other gets therapy alone. Researchers will track ch…

This study tests whether a nasal spray containing oxytocin, often called the 'love hormone,' can help adults with binge-eating disorder eat less often in binges. About 60 adults will receive either oxytocin or a placebo spray daily for 8 weeks. The goal is to see if oxytocin redu…

This study tests whether a type of talk therapy called Acceptance and Commitment Therapy (ACT) can help people with type 1 diabetes who also have an eating disorder. About 235 people aged 16-50 will be assigned to ACT, supportive diabetes counseling, or a waitlist. The goal is to…

This study tests whether a virtual reality (VR) tool that resets the body's internal clock can improve sleep and reduce binge eating. Forty adults with binge eating disorder will use a VR headset for 10 minutes twice daily for one month. One group gets the active reset technology…

This study tests a mobile app called FoodTraining that trains people to better control their responses to food. It is for adults with obesity, binge-eating disorder, or bulimia who are already receiving standard treatment. Participants use the app for 4 weeks alongside their usua…

This study tests whether watching weekly video lessons instead of reading text can help adults with binge eating disorder stop binge eating. Eighty participants will receive either video or text-based therapy plus brief online guidance sessions. The goal is to see if video lesson…

This study tests two versions of cognitive behavioral therapy (CBT) delivered online for veterans and underrepresented Americans with binge-eating disorder or bulimia. About 144 participants will receive either therapist-led or self-help CBT through VA telehealth. The goal is to …

This study is testing a brief online program called COR for adults who struggle with binge eating. The program includes eight weekly sessions focused on emotions, body awareness, and eating habits. Researchers want to see if people find the program helpful and easy to stick with.…

This study is creating and testing a friendly AI chatbot that talks with teens and young adults (ages 12-26) who have eating disorders like anorexia or bulimia. The chatbot is used alongside their regular treatment to help them feel less scared about gaining weight. About 20 peop…

This study is testing a mobile app designed to help teenagers who struggle with binge eating and are overweight or at risk for it. The app uses proven strategies to improve self-control and eating habits. For 16 weeks, 50 teens will use the app and share their thoughts on how hel…

This study tests whether a 16-session digital program that combines mindfulness with cognitive behavioral therapy can help adults with binge eating disorder. Forty participants will either receive the combined program or a simpler self-monitoring tool. The goal is to see if the a…

This study tests a mobile app called BEST-U that provides guided self-help therapy to university students struggling with binge eating. Researchers will compare the app to a different type of talk therapy in 74 students. The goal is to see if the app can reduce binge eating and i…

This study follows 180 children with overweight or obesity to see how their thinking skills (like memory and self-control) relate to their eating behaviors and weight changes over time. Researchers will use brain games and interviews to measure these skills. The goal is to find b…