BINGE EATING DISORDER

This Phase 3 trial is testing whether solriamfetol, a drug already approved for sleep disorders, can reduce binge eating episodes in adults with binge eating disorder. About 450 participants will receive either solriamfetol or a placebo daily for 12 weeks. The main goal is to see…

This phase 2 trial tests whether tirzepatide, a drug used for diabetes and weight loss, can reduce binge-eating episodes and help with weight loss in adults with obesity and binge-eating disorder. About 105 participants will receive tirzepatide, a placebo, or the existing drug li…

This study looks at whether adding GLP-1 weight-loss drugs to cognitive behavioral therapy helps adults with severe obesity and binge eating disorder. About 80 participants will either take a GLP-1 drug or not, while both groups attend therapy sessions. Researchers will track cha…

This study tests whether a nasal spray containing oxytocin (a natural hormone) can help adults with binge-eating disorder eat less often in binges. About 60 adults will receive either the oxytocin spray or a placebo for 8 weeks. Researchers will track changes in binge frequency a…

This study tests a brief online program called COR for adults who struggle with binge eating. The program includes eight weekly sessions that teach skills to manage emotions and reconnect with eating in a healthy way. Researchers want to see if people find the program helpful and…

This study tests a virtual reality (VR) headset that uses circadian reset technology to improve sleep and reduce binge eating in 40 adults with binge eating disorder. Participants use the headset for 10 minutes twice daily for one month. Researchers will compare changes in binge …

This study is testing an AI-powered chatbot called Exp-ED that guides teens and young adults through exposure therapy exercises to reduce anxiety about weight gain. Twenty participants in a partial hospitalization program for eating disorders will use the app for six weeks. Resea…

This study tests whether a type of talk therapy called Acceptance and Commitment Therapy (ACT) can help people with type 1 diabetes who also have eating disorders. Participants will be randomly assigned to ACT, supportive diabetes counseling, or a waitlist. The goal is to see if …

This study tests a mobile app called BEST-U that helps university students reduce binge eating. About 74 students with binge-eating disorder or bulimia will use the app or a comparison therapy. The goal is to see if the app makes it easier for students to get effective help witho…

This study tests a mobile app called FoodTraining that trains people to resist food cues. About 113 adults with obesity, bulimia, or binge-eating disorder will use the app for 4 weeks alongside their usual treatment. Researchers will measure changes in emotional eating and uncont…

This study tests whether virtual cognitive behavioral therapy (CBT) can help reduce binge eating and bulimia symptoms in veterans and other underrepresented groups. About 144 adults with binge eating disorder or bulimia will receive therapist-led or self-help CBT via telehealth. …

This study tests whether a 16-session digital program that combines mindfulness with cognitive-behavioral therapy (CBT) is acceptable and practical for adults with binge eating disorder. Forty participants will be randomly assigned to the combined program or a simpler self-monito…

This early study tests a new therapy called PRIDE for sexual minority individuals (lesbian, gay, bisexual, etc.) who have an eating disorder. The therapy aims to reduce internalized stigma and improve coping with stress related to their identity. Thirty participants will attend u…

This study is testing a smartphone app that uses brief surveys and phone sensor data to detect when someone with an eating disorder might be at higher risk for behaviors like binge eating, restricting food, or purging. The app then delivers short video lessons on coping skills. T…

This study takes gut bacteria from women with eating disorders (like anorexia or bulimia) and gives them to mice to see if the mice gain or lose weight differently. The goal is to understand if an unhealthy gut microbiome can influence body weight and eating behavior. It's a basi…