B CELL MALIGNANCIES
Clinical trials for B CELL MALIGNANCIES explained in plain language.
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New CAR T-Cell therapy targets tough blood cancers
Disease control Not yet recruitingThis study tests a new treatment called SHB-02-CD19 for people with certain blood cancers (B-cell malignancies) that have come back or not responded to standard treatments. The therapy uses the patient's own immune cells, modified to recognize and attack cancer cells. The study a…
Matched conditions: B CELL MALIGNANCIES
Phase: PHASE1, PHASE2 • Sponsor: Sheba Medical Center • Aim: Disease control
Last updated Jun 16, 2026 12:51 UTC
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Double-Pronged CAR t cells take aim at Hard-to-Treat blood cancers
Disease control Not yet recruitingThis early-stage trial tests a new type of CAR T cell therapy that targets two proteins (CD19 and CD20) on cancer cells. It is for adults with B cell leukemia or lymphoma who have run out of standard options, including commercial CAR T cells. The main goal is to check the safety …
Matched conditions: B CELL MALIGNANCIES
Phase: PHASE1 • Sponsor: University Hospital, Basel, Switzerland • Aim: Disease control
Last updated Jun 15, 2026 18:54 UTC
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New drug HRS-1635 enters early human testing for hard-to-treat blood cancers
Disease control Not yet recruitingThis early-phase study tests the safety and tolerability of a new drug called HRS-1635 in 180 adults with B-cell blood cancers that have come back or not responded to treatment. Researchers will find the best dose and watch for side effects. The goal is to control the disease, no…
Matched conditions: B CELL MALIGNANCIES
Phase: PHASE1 • Sponsor: Chengdu Suncadia Medicine Co., Ltd. • Aim: Disease control
Last updated Jun 12, 2026 12:04 UTC
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MRNA cancer therapy takes on tough blood cancers
Disease control Not yet recruitingThis early-phase study tests a new mRNA drug (WGb-0301) for people with B-cell blood cancers that have come back or not responded to standard treatments. The drug uses lipid nanoparticles to deliver mRNA that targets CD19 on cancer cells, aiming to clear them. Nine participants w…
Matched conditions: B CELL MALIGNANCIES
Phase: EARLY_PHASE1 • Sponsor: Sichuan University • Aim: Disease control
Last updated Jun 10, 2026 13:26 UTC
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Scientists investigate immune 'Brakes' in blood cancers
Knowledge-focused Not yet recruitingThis study looks at two proteins, CD85d and CD305, that act like brakes on the immune system. Researchers want to see how these proteins behave in different types of B-cell cancers. They will measure these proteins in 180 newly diagnosed patients to learn if they can predict how …
Matched conditions: B CELL MALIGNANCIES
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:06 UTC
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Scientists probe immune markers to unlock secrets of b-cell cancers
Knowledge-focused Not yet recruitingThis study will measure two immune system markers, CD274 and CD276, in people newly diagnosed with B-cell cancers like leukemia and lymphoma. The goal is to understand how these markers affect the body's ability to fight cancer and why some treatments stop working. The study does…
Matched conditions: B CELL MALIGNANCIES
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:07 UTC