AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD)
Clinical trials for AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD) explained in plain language.
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Could a drug for acromegaly protect kidneys in polycystic disease?
Disease control CompletedThis Phase 3 trial tested whether lanreotide, a drug that blocks certain growth hormones, can slow the loss of kidney function in people with autosomal dominant polycystic kidney disease (ADPKD). The study included 159 adults with moderate kidney decline. Participants received ei…
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD)
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Large study tracks kidney disease progression in thousands of patients
Knowledge-focused CompletedThis study followed over 3,400 people with autosomal dominant polycystic kidney disease (ADPKD) to learn how the disease progresses. Researchers measured kidney size, symptoms, quality of life, and healthcare costs. The goal was to identify factors that predict faster disease pro…
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD)
Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Drug interaction study: VX-407 and oral contraceptives
Knowledge-focused CompletedThis study looked at how a new drug called VX-407 changes the way birth control pills work in the body. 74 healthy adults took VX-407 along with different types of oral contraceptives. The goal was to see if VX-407 affects the levels of these contraceptives, which is important fo…
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD)
Phase: PHASE1 • Sponsor: Vertex Pharmaceuticals Incorporated • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Healthy volunteers test new drug for kidney disease
Knowledge-focused CompletedThis early-stage study tested the safety and how the body handles a new drug called VX-407 in 32 healthy adults. The goal was to check for side effects and measure drug levels in the blood. No treatment benefit was expected, as this study was designed to gather safety information…
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD)
Phase: PHASE1 • Sponsor: Vertex Pharmaceuticals Incorporated • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Tiny gene study may unlock clues to kidney disease in bergamo families
Knowledge-focused CompletedThis study examined 10 people with autosomal dominant polycystic kidney disease (ADPKD) to see if a specific deletion in the PKD2 gene is shared among families in the Bergamo area. Researchers interviewed participants and built family trees to understand how the gene change affec…
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD)
Sponsor: Mario Negri Institute for Pharmacological Research • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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530 canadians with kidney disease share real-world drug results
Knowledge-focused CompletedThis study followed 530 adults with autosomal dominant polycystic kidney disease (ADPKD) who were already taking the drug tolvaptan (JINARC™). Researchers wanted to see how the medication affected their quality of life, pain, and daily activities, as well as how long it took befo…
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD)
Sponsor: Otsuka Canada Pharmaceutical Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC