ARDS

This early-stage study tests a single dose of AVM0703 in 16 adults with severe breathing failure (ARDS) caused by COVID-19 or influenza. The main goal is to check safety and find the right dose. Participants are randomly assigned to get the drug or a placebo, and no one knows who…

This study tests whether the drug fostamatinib is safe and helpful for adults hospitalized with acute respiratory distress syndrome (ARDS), a severe lung injury that makes breathing very difficult. About 40 participants will receive either the drug or a placebo, and researchers w…

This study will create a registry of up to 1,000 ICU patients who need a breathing machine. Doctors will use a non-invasive imaging tool called Electrical Impedance Tomography (EIT) to monitor lung function in real time. The goal is to track how EIT is used and whether it helps g…

This study looks at 377 adults with severe lung failure (ARDS) who are placed on their stomachs to help them breathe. Researchers will use computer models to predict which patients are most likely to die in the ICU. The goal is to help doctors make better treatment decisions for …

This study looks at how different levels of pressure from a breathing machine affect the heart in people with moderate-to-severe acute respiratory distress syndrome (ARDS). Researchers will test three pressure settings in 20 patients to see how lung collapse and overstretching im…