ARDS

This study tests whether the drug fostamatinib can safely help adults hospitalized with acute respiratory distress syndrome (ARDS), a severe lung injury. About 40 participants will receive either the drug or a placebo, and researchers will track serious side effects for 30 days. …

This early-stage study tests a single dose of a new drug called AVM0703 in 16 adults with severe breathing failure (ARDS) caused by COVID-19 or the flu. The main goal is to check if the drug is safe and how the body processes it. Participants are randomly assigned to receive the …

This study looks at whether a simple blood test, called the fibrinogen-to-albumin ratio, can predict if someone with a traumatic brain injury will develop acute respiratory distress syndrome (ARDS), a serious lung condition. Researchers will measure these proteins in the blood of…

This study tests a mobile mindfulness program called Lift for people who survived a serious illness in the ICU and now struggle with depression, anxiety, or stress. About 450 adults will use either the Lift app or a health education app for 6 months. The goal is to see if the min…

This study looks at 377 adults with severe lung failure (ARDS) who were treated with prone positioning (lying face down to help breathing). Researchers will use computer models to predict which patients are at highest risk of dying in the ICU. The goal is to help doctors make bet…

This study looks at how different levels of ventilator pressure affect the heart and lungs in 20 patients with moderate-to-severe ARDS. Researchers will test three pressure settings to see which one best balances lung collapse and overstretching while keeping the heart pumping we…

This study will create a registry of up to 1,000 ICU patients who are monitored with a non-invasive lung imaging device called Electrical Impedance Tomography (EIT). The device helps doctors see how well the lungs are working and guide breathing support. Researchers will track ou…