AORTIC STENOSIS, SEVERE
Clinical trials for AORTIC STENOSIS, SEVERE explained in plain language.
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New heart valve could save lives without Open-Heart surgery
Disease control OngoingThis trial is testing a new heart valve called SAPIEN X4/X4S in over 1,200 people with severe aortic stenosis, a condition where the heart's aortic valve narrows. The valve is inserted through a catheter, avoiding open-heart surgery. Researchers are measuring how many patients di…
Matched conditions: AORTIC STENOSIS, SEVERE
Phase: NA • Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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Can TAVI be done safely without a surgery team on standby?
Knowledge-focused OngoingThis study looks at whether a heart valve replacement procedure called TAVI can be safely performed in hospitals that do not have on-site cardiac surgery backup. It involves 657 patients with severe aortic stenosis who are at high risk for surgery. The same experienced doctors pe…
Matched conditions: AORTIC STENOSIS, SEVERE
Phase: NA • Sponsor: Azienda Usl di Bologna • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC