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Clinical trials for AMD explained in plain language.
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One-Shot gene therapy aims to free patients from monthly eye injections
Disease control Recruiting nowThis study is testing a one-time gene therapy called RGX-314 for people with wet age-related macular degeneration (wet AMD), a leading cause of vision loss. The goal is to see if this single treatment can help the eye make its own medicine to control the disease, potentially redu…
Matched conditions: AMD
Phase: PHASE2, PHASE3 • Sponsor: AbbVie • Aim: Disease control
Last updated Apr 01, 2026 22:47 UTC
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One-Shot gene therapy could end decades of eye injections for millions
Disease control Recruiting nowThis study is testing a one-time gene therapy called RGX-314 for people with wet age-related macular degeneration (wet AMD), a leading cause of vision loss. The goal is to see if this single treatment can help control the disease long-term, potentially freeing patients from the b…
Matched conditions: AMD
Phase: PHASE3 • Sponsor: AbbVie • Aim: Disease control
Last updated Mar 11, 2026 14:53 UTC
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Tiny eye telescope aims to restore sight for severe AMD
Symptom relief Recruiting nowThis study is testing a small telescope-like device that is implanted inside the eye during cataract surgery. It is designed to improve central vision for people who have lost it due to the most advanced stage of age-related macular degeneration (AMD). About 76 participants will …
Matched conditions: AMD
Phase: NA • Sponsor: VisionCare, Inc. • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Could treating sinus problems help save eyesight?
Knowledge-focused Recruiting nowThis study aims to understand if there is a connection between sinus infections and a severe form of age-related macular degeneration (AMD), a leading cause of vision loss. Researchers will check 200 patients with wet AMD for sinusitis. They want to see if treating the sinus infe…
Matched conditions: AMD
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Scientists build 'Disease-in-a-Dish' to hunt for blindness cures
Knowledge-focused Recruiting nowThis study aims to understand and eventually find treatments for serious eye diseases that can lead to blindness, like macular degeneration. Researchers will collect simple samples like hair, skin, or blood from people with these conditions and from healthy volunteers. In the lab…
Matched conditions: AMD
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:18 UTC