AGE RELATED MACULAR DEGENERATION (AMD)

This study tests an experimental eye injection called ONL1204 in 324 adults aged 55 and older with geographic atrophy, a severe form of dry age-related macular degeneration that causes blind spots. The goal is to see if the drug can slow the growth of damaged areas in the retina …

This study tests a small telescope implant (SING IMT) for people with advanced age-related macular degeneration (AMD) who have stable but severe central vision loss in both eyes. About 44 participants aged 55 and older will receive the implant in one eye to see if it safely impro…

This study tests whether an oral drug called dimethyl fumarate (Tecfidera) can safely slow the growth of geographic atrophy, a form of advanced age-related macular degeneration that causes vision loss. About 90 adults aged 55–85 with geographic atrophy will take the drug for 12 m…

This study tests two experimental drugs, pozelimab and cemdisiran, given as shots under the skin, to see if they can slow the growth of blind spots in people with geographic atrophy, a late stage of dry age-related macular degeneration. About 975 adults with moderate vision loss …

This study tests whether an AI tool (VeriSee) can help doctors detect two common causes of vision loss—diabetic retinopathy and age-related macular degeneration—earlier than standard exams. About 4,300 adults with diabetes or aged 50+ will be randomly assigned to AI-assisted scre…

This study tests whether a 6-month online spin cycling program can improve vision and daily function in veterans aged 65-89 with intermediate age-related macular degeneration (AMD). Participants will join group spinning classes from home and have their eyesight, thinking, and phy…

This study looks at how well a high-dose eye injection (Eylea 8mg) works in the first two months for people with wet age-related macular degeneration, a condition that causes vision loss. Researchers will use eye scans to measure fluid changes and vision improvements in 50 partic…

This study aims to find protein markers in blood and eye fluids that can help identify and track three major eye diseases: age-related macular degeneration, diabetic retinopathy, and retinal detachment. About 260 adults with and without these conditions will provide samples durin…

This study looks at new ways to measure how well the eye adapts to darkness in people with early age-related macular degeneration (AMD). Researchers want to see if these tests are reliable and can track changes over time. The goal is to create better tools for future treatment st…