ADVANCED SOLID MALIGNANCIES
Clinical trials for ADVANCED SOLID MALIGNANCIES explained in plain language.
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Could a simple shot replace IV drips for some cancer patients?
Disease control OngoingThis early-stage trial is testing whether amivantamab, a drug that targets specific proteins on cancer cells, can be given as a shot under the skin instead of through an IV. About 158 adults with advanced solid tumors (like lung or head and neck cancers) will receive different do…
Matched conditions: ADVANCED SOLID MALIGNANCIES
Phase: PHASE1 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Experimental cocktail aims to shrink tough tumors
Disease control OngoingThis early-phase trial tests a combination of two immune-boosting drugs (tiragolumab and atezolizumab) plus a special type of radiation (RadScopal) in 7 adults with advanced solid tumors that have not responded to standard treatments. The main goal is to check safety and side eff…
Matched conditions: ADVANCED SOLID MALIGNANCIES
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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New cancer drug saruparib enters early human testing
Disease control OngoingThis early-stage trial is testing a new drug, saruparib, in 41 people with advanced solid tumors that have not responded to standard treatments. The main goals are to check the drug's safety, how it interacts with other common medications, and how well different pill versions wor…
Matched conditions: ADVANCED SOLID MALIGNANCIES
Phase: PHASE1 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New pill takes on Hard-to-Treat cancers in first human trial
Disease control OngoingThis early-stage trial tests an experimental oral drug called PRJ1-3024 in 39 adults with advanced solid tumors that have not responded to standard treatments. The main goal is to check safety and find the right dose. Researchers will also look for early signs that the drug may s…
Matched conditions: ADVANCED SOLID MALIGNANCIES
Phase: PHASE1 • Sponsor: Zhuhai Yufan Biotechnologies Co., Ltd • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New cancer drug BR115 enters first human tests
Disease control TerminatedThis early-phase study tests a new drug called BR115 in 120 people with advanced solid tumors that have not responded to other treatments. The main goal is to check safety and find the right dose. Participants receive the drug weekly after an initial two doses, and the study moni…
Matched conditions: ADVANCED SOLID MALIGNANCIES
Phase: PHASE1 • Sponsor: BioRay Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC