ADVANCED SOLID MALIGNANCIES

This is the first time a new drug called BR115 is being tested in people. The main goal is to check its safety and see how the body handles it in 120 patients with advanced solid cancers that have progressed despite standard care. Researchers will also look for any early signs th…

This is the first-ever study in humans of a new oral medication called PRJ1-3024 for people with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find a safe dose and see how the body handles the drug. Researchers will also look for…

This study is testing a new, easier way to give the cancer drug amivantamab—as a simple injection under the skin instead of a long IV infusion. It aims to find a safe and effective dose for this new method in people with advanced solid tumors who have few other treatment options.…

This early-stage study is testing the safety of a new combination treatment for people with advanced solid tumors that have spread. The treatment combines two immunotherapy drugs with a special type of targeted radiation. It is for patients who have very limited life expectancy a…

This early-stage study aims to understand how a new oral drug called saruparib interacts with other common medications in patients with advanced solid tumors. It will also test if different ways of making the pill affect how the body absorbs it. The main goal is to gather safety …