ADVANCED SOLID MALIGNANCIES
Clinical trials for ADVANCED SOLID MALIGNANCIES explained in plain language.
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New hope for Hard-to-Treat cancers: first human trial launches
Disease control OngoingThis early-stage study tests a new drug called PRJ1-3024 in about 39 adults with advanced solid tumors that have stopped responding to standard treatments. The main goal is to check the drug's safety and find the right dose. Researchers will also look for signs that the drug migh…
Matched conditions: ADVANCED SOLID MALIGNANCIES
Phase: PHASE1 • Sponsor: Zhuhai Yufan Biotechnologies Co., Ltd • Aim: Disease control
Last updated May 17, 2026 06:21 UTC
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New cancer drug BR115 enters first human tests for advanced solid tumors
Disease control TerminatedThis early-stage study tests a new drug, BR115, in 120 people with advanced solid tumors that have not responded to other treatments. The main goal is to check the drug's safety and how the body processes it. Participants receive the drug weekly after an initial two doses in the …
Matched conditions: ADVANCED SOLID MALIGNANCIES
Phase: PHASE1 • Sponsor: BioRay Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated May 17, 2026 06:17 UTC
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Triple threat: new combo therapy targets Hard-to-Treat cancers
Disease control OngoingThis early-phase trial tests a combination of two immunotherapy drugs (tiragolumab and atezolizumab) plus a special type of radiation (RadScopal) in people with advanced solid tumors that have not responded to standard treatments. The study aims to see if this triple therapy is s…
Matched conditions: ADVANCED SOLID MALIGNANCIES
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 17, 2026 06:14 UTC
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Could a simple shot replace IV drips for some cancer patients?
Disease control OngoingThis early-stage study tests if amivantamab, a drug that targets certain cancer cells, can be given as a shot under the skin instead of through an IV. It includes 158 adults with advanced solid tumors like lung or head and neck cancer. The main goals are to check safety, find the…
Matched conditions: ADVANCED SOLID MALIGNANCIES
Phase: PHASE1 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated May 05, 2026 11:53 UTC
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New study checks Saruparib's drug interactions in advanced cancer patients
Knowledge-focused OngoingThis early-stage study looks at how the experimental drug saruparib affects other medicines in people with advanced solid tumors that have not responded to standard treatments. About 41 participants will take saruparib along with common drugs to see if it changes their levels in …
Matched conditions: ADVANCED SOLID MALIGNANCIES
Phase: PHASE1 • Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated May 11, 2026 20:41 UTC