Experimental cocktail aims to shrink tough tumors
NCT ID NCT06760481
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial tests a combination of two immune-boosting drugs (tiragolumab and atezolizumab) plus a special type of radiation (RadScopal) in 7 adults with advanced solid tumors that have not responded to standard treatments. The main goal is to check safety and side effects, while also looking for signs that the tumors shrink. Because it is a very small, first-in-human study, the results will only show whether the approach is safe enough to test further.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Tiragolumab, Atezolizumab, and Radiation Therapy
What this could lead to
If this combination proves safe and effective, it could offer a new treatment option for people with advanced solid tumors who have run out of standard therapies.
What could go wrong
This is a very early, small Phase I trial with only 7 participants, so results may not apply broadly. The main goal is safety, not yet proof of benefit, and side effects from the drug combination or radiation could be significant.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The University of Texas M. D. Anderson Cancer Center
Houston, Texas, 77030, United States