ADVANCED SOLID CANCER
Clinical trials for ADVANCED SOLID CANCER explained in plain language.
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New drug combo aims to fight advanced cancers in first human trial
Disease control Recruiting nowThis early-phase study tests a new experimental drug (BI 3819026) alone and with another drug (ezabenlimab) in adults with advanced solid cancers that have not responded to standard treatments. The main goal is to find the safest dose and check for side effects. About 60 particip…
Matched conditions: ADVANCED SOLID CANCER
Phase: PHASE1 • Sponsor: Boehringer Ingelheim • Aim: Disease control
Last updated Aug 06, 2026 00:00 UTC
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Can a pill that blocks multiple cancer proteins shrink Hard-to-Treat tumors?
Disease control Recruiting nowThis early-phase trial is testing an experimental oral drug called APG-2449 in people with advanced solid tumors, including certain lung cancers, mesothelioma, esophageal cancer, and ovarian cancer. APG-2449 is designed to block several proteins (FAK, ALK, and ROS1) that help can…
Matched conditions: ADVANCED SOLID CANCER
Phase: PHASE1 • Sponsor: Ascentage Pharma Group Inc. • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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New experimental drug SIM0613 enters first human tests for advanced cancers
Disease control Recruiting nowThis early-stage trial tests a new drug called SIM0613 in about 294 adults with advanced solid tumors that have worsened after standard treatments. The study has two parts: first, finding a safe dose, then expanding to see if the drug shrinks tumors. The main goals are safety and…
Matched conditions: ADVANCED SOLID CANCER
Phase: PHASE1 • Sponsor: Jiangsu Simcere Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New hope for advanced cancer patients: first human trial of SIM0609 begins
Disease control Recruiting nowThis early-phase study tests a new drug called SIM0609 in adults with advanced solid tumors that have not responded to standard treatments. The main goals are to check the drug's safety, find the right dose, and see if it can shrink tumors. About 232 participants will take part a…
Matched conditions: ADVANCED SOLID CANCER
Phase: PHASE1 • Sponsor: Jiangsu Simcere Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Poop pills plus immunotherapy: new hope for stubborn cancers?
Disease control Recruiting nowThis study tests whether a fecal microbiota transplant (FMT) combined with the immunotherapy drug nivolumab can help people with advanced solid cancers that stopped responding to prior treatment. About 50 participants will receive the combination to see if it can shrink tumors. T…
Matched conditions: ADVANCED SOLID CANCER
Phase: NA • Sponsor: Asan Medical Center • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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New drug combo targets Hard-to-Treat cancers
Disease control Recruiting nowThis early-stage study tests a new drug, APX-343A, alone or with another cancer drug (pembrolizumab) in people with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety, find the best dose, and see if the drug shrinks tumors. Ab…
Matched conditions: ADVANCED SOLID CANCER
Phase: PHASE1 • Sponsor: Aptabio Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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New hope for advanced cancer? experimental drug MHB046C enters human trials
Disease control Recruiting nowThis study tests a new drug called MHB046C in 200 people with advanced solid tumors that no longer respond to standard treatments. The goal is to find a safe dose and see if the drug can shrink tumors. Participants receive the drug intravenously every three weeks.
Matched conditions: ADVANCED SOLID CANCER
Phase: PHASE1, PHASE2 • Sponsor: Minghui Pharmaceutical (Hangzhou) Ltd • Aim: Disease control
Last updated Jun 26, 2026 18:36 UTC