ACUTE LYMPHOBLASTIC LEUKEMIA, PEDIATRIC
Clinical trials for ACUTE LYMPHOBLASTIC LEUKEMIA, PEDIATRIC explained in plain language.
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Engineered immune cells take aim at tough childhood cancers
Disease control CompletedThis early-phase trial tested whether a new type of immune cell therapy (CD22 CAR T cells) could be safely made and given to 10 children and young adults whose B-cell leukemia or lymphoma had come back or stopped responding to treatment. The therapy uses the patient's own immune …
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA, PEDIATRIC
Phase: PHASE1 • Sponsor: Kara Lynn Davis • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New drug combo tested for tough childhood leukemia
Disease control CompletedThis early-phase study tested whether adding the targeted drug palbociclib to standard chemotherapy is safe for children with acute lymphoblastic leukemia that has returned or not responded to treatment. Only 2 children took part, and the main goal was to find the highest tolerab…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA, PEDIATRIC
Phase: PHASE1 • Sponsor: Tanja Andrea Gruber • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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Gene test spots hidden leukemia in kids
Knowledge-focused CompletedThis study looked at 148 children with T-cell acute lymphoblastic leukemia to see if a high-tech gene test could find tiny amounts of cancer left after treatment. Researchers used next-generation sequencing to check for specific gene changes in immune cells. They then compared th…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA, PEDIATRIC
Sponsor: The Children's Hospital of Zhejiang University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Leukemia Survivors' immunity under the microscope
Knowledge-focused CompletedThis study followed 89 children who finished chemotherapy for acute lymphoblastic leukemia (ALL) to see how their immune systems bounced back. Researchers measured antibody levels for vaccine-preventable diseases and tracked infections during the first year off treatment. The goa…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA, PEDIATRIC
Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC