ACHALASIA
Clinical trials for ACHALASIA explained in plain language.
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No-Scalpel fix for swallowing disorder tracked in massive study
Disease control ENROLLING_BY_INVITATIONThis study is tracking 5,000 adults with achalasia, a condition where the esophagus fails to relax and push food into the stomach. All participants are treated with POEM, a procedure that uses an endoscope to cut the tight muscle without any incisions on the body. Researchers wil…
Matched conditions: ACHALASIA
Sponsor: Indiana University • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Could adding a balloon stretch to botox help achalasia patients swallow better?
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether combining Botox injections with a balloon dilation of the esophagus works better than Botox alone for people with achalasia, a rare swallowing disorder. The trial enrolls 50 adults who are not healthy enough for more invasive treatments. Participants a…
Matched conditions: ACHALASIA
Phase: PHASE4 • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Painkiller-Sparing nerve block trial pulled before it began
Symptom relief TerminatedThis study planned to test a laparoscopic-guided nerve block (TAP block) to reduce opioid painkiller use after weight-loss or anti-reflux stomach surgeries. It compared two numbing medicines, Bupivacaine HCL and Exparel. However, the trial was withdrawn before enrolling any parti…
Matched conditions: ACHALASIA
Phase: PHASE2, PHASE3 • Sponsor: Baylor Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Researchers track recovery after keyhole surgery for swallowing disorders
Knowledge-focused OngoingThis study follows 200 patients who had minimally invasive surgery for conditions like achalasia, GERD, or hiatal hernia. Each year, patients fill out questionnaires about their symptoms and quality of life, and doctors review their medical records. The goal is to understand how …
Matched conditions: ACHALASIA
Sponsor: Ottawa Hospital Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Tiny tools, big promise: endoscopic procedures take on major GI surgery
Knowledge-focused ENROLLING_BY_INVITATIONThis study tracks 500 adults with conditions like acid reflux, achalasia, or complications after weight-loss surgery. Participants choose either a newer endoscopic procedure (done through a scope) or standard surgery. Researchers will compare how well each approach controls sympt…
Matched conditions: ACHALASIA
Phase: NA • Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC