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Wolfram syndrome 1

MONDO:0009101

Any Wolfram syndrome in which the cause of the disease is a mutation in the WFS1 gene.

Also known as: WFS1, WFS1 Wolfram syndrome, Wolfram syndrome 1, Wolfram syndrome caused by mutation in WFS1, Wolfram syndrome type 1, WOLFRAM syndrome 1, Wfs, diabetes insipidus and mellitus with optic atrophy and deafness

1 clinical trial for this condition and its sub-types.

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Broader categories

Disease (618) Hereditary disease (172) Syndromic disease (24) Human disease (14) Wolfram syndrome (7) Disease of genetic or genomic mechanism (2) Disease by body system or component (0) Disease by etiologic mechanism (0) WFS1-related disorder (0)
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  • Are these two eye diseases actually the same? new study aims to find out

    Knowledge-focused Not yet recruiting

    This study will look back at medical records of 45 people with either Wolfram syndrome or a related eye condition caused by changes in the WFS1 gene. Researchers want to see if these two conditions are truly different by comparing vision loss over time and other health problems. …

    Sponsor: Hôpital Necker-Enfants Malades • Aim: Knowledge-focused

    Last updated Jun 27, 2026 08:10 UTC

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