Von Willebrand disease type 2B
MONDO:0015629A subtype of type 2 VWD characterized by a bleeding disorder associated with an increase in the affinity of the Willebrand factor (von Willebrand factor; VWF) for platelets. This anomaly results in spontaneous binding of high molecular weight VWF multimers to platelets leading to rapid clearance of both the platelets (increasing the risk of thrombocytopenia) and the high molecular weight VWF multimers from the plasma.
Also known as: von Willebrand disease type 2B, von Willebrand disease, type 2B
47 clinical trials for this condition and its sub-types.
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Disease
(618)
Hereditary disease
(172)
Hematologic disorder
(160)
Hemorrhagic disease
(100)
Blood coagulation disease
(51)
Von Willebrand disease (hereditary or acquired)
(37)
Hereditary von Willebrand disease
(17)
Human disease
(14)
Coagulation protein disease
(12)
Inherited blood coagulation disorder
(7)