Von Willebrand disease type 2B
MONDO:0015629A subtype of type 2 VWD characterized by a bleeding disorder associated with an increase in the affinity of the Willebrand factor (von Willebrand factor; VWF) for platelets. This anomaly results in spontaneous binding of high molecular weight VWF multimers to platelets leading to rapid clearance of both the platelets (increasing the risk of thrombocytopenia) and the high molecular weight VWF multimers from the plasma.
Also known as: von Willebrand disease type 2B, von Willebrand disease, type 2B
14 clinical trials for this condition and its sub-types.
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New clotting factor combo aims to tame von willebrand bleeding
Disease control OngoingThis study looks at how well Eqwilate, a concentrated mix of two clotting proteins (VWF and FVIII), controls bleeding in people with von Willebrand disease. It includes patients aged 6 and older who use Eqwilate on demand, before surgery, or as regular prevention. Researchers tra…
Sponsor: Octapharma • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC
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AI takes on blood clotting: can ChatGPT guide surgeons on bleeding?
Knowledge-focused TerminatedThis study evaluates whether artificial intelligence models can accurately interpret ROTEM blood clotting tests and recommend treatments for coagulopathy. Researchers will compare AI decisions to those of a panel of clinical experts using data from adults undergoing elective card…
Sponsor: Ondokuz Mayıs University • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC