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Vitiligo
MONDO:0008661Generalized well circumscribed patches of leukoderma that are generally distributed over symmetric body locations and is due to autoimmune destruction of melanocytes.
137 clinical trials for this condition and its sub-types.
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Broader categories
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New cream aims to stop vitiligo relapse after repigmentation
Disease control TerminatedThis trial tested a cosmetic cream called RV5098A to see if it could help adults with vitiligo keep their facial pigmentation after successful repigmentation treatment. Vitiligo causes white patches on the skin, and even after treatment, about 40% of people lose color again withi…
Sponsor: Pierre Fabre Dermo Cosmetique • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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New gel shows promise for vitiligo, but study halted early
Disease control TerminatedThis study tested a gel called VYN201 for people with non-segmental vitiligo, a condition that causes white patches on the skin. The goal was to see if the gel could reduce the size of these patches over 24 weeks. The trial involved 205 adults aged 18 to 75, but it was terminated…
Phase: PHASE2 • Sponsor: Vyne Therapeutics Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New hope for vitiligo: experimental drug aims to restore skin color
Disease control TerminatedThis study tested an experimental drug called MK-6194 in adults with non-segmental vitiligo, a condition that causes white patches on the skin. The goal was to see if the drug could safely reduce the amount of vitiligo on the face compared to a placebo. The trial was stopped earl…
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Biopsy tolerance study ends early – what we know
Knowledge-focused TerminatedThis study aimed to understand how well patients tolerate biopsies for autoimmune diseases and whether they feel properly informed. It planned to enroll 505 people but was terminated early. The results may help improve patient experience with these common procedures.
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Skin microbes linked to vitiligo and immunotherapy reactions in melanoma patients
Knowledge-focused TerminatedThis study explores whether the community of bacteria living on the skin (the skin microbiome) plays a role in vitiligo—a condition that causes white patches—and in side effects from anti-PD-1 immunotherapy for advanced melanoma. Researchers will collect skin swabs from people wi…
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC