Type 1 interferonopathy
MONDO:0700264Conditions in which increased type 1 interferon signaling leads to autoimmune and neurological disorders. These disorders are caused by variants in genes involved in nucleic acid metabolism, sensing, and the innate immune response.
31 clinical trials for this condition and its sub-types.
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Broader categories
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Can a Drug-Radiation combo outsmart Treatment-Resistant colorectal cancer?
Disease control Not yet recruitingThis phase 2 trial is testing whether combining an experimental drug called S-531011 with a precise radiation technique known as RadScopal can help control metastatic colorectal cancer that has not responded to prior treatments. The study enrolls about 30 adults with advanced dis…
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
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Sniffing out breastfeeding: scientists decode Baby's nose
Knowledge-focused Not yet recruitingThis study looks at how smell helps newborns find and latch onto the breast for breastfeeding. Researchers will use a special machine to track odors from mothers and babies in real time. The goal is to understand the role of scent in early bonding and feeding, which could help im…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Teen depression study tracks heartbeats and family bonds
Knowledge-focused Not yet recruitingThis study looks at how heart rate variability (a measure of stress response) relates to emotional control and parent-teen relationships in 74 adolescents with depression. Teens will wear a Fitbit while sleeping for a week and fill out questionnaires. The goal is to better unders…
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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New blood tests aim to unlock mysteries of rare inflammatory diseases
Knowledge-focused Not yet recruitingThis study aims to better understand rare autoinflammatory diseases by developing blood tests that measure inflammation markers. Researchers will analyze blood samples from 60 adults and children with these conditions. The goal is to identify specific inflammation pathways, which…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:44 UTC