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Toxic epidermal necrolysis

MONDO:0019810

Toxic epidermal necrolysis (TEN) is an acute and severe skin disease with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes.

Also known as: SJS-TEN, TEN, toxic epidermolysis, Lyell syndrome, Lyell's syndrome, Stevens-Johnson syndrome/toxic epidermal necrolysis spectrum

14 clinical trials for this condition and its sub-types.

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Sub-types

Stevens-Johnson syndrome (9) Lyell syndrome (0) Stevens-Johnson syndrome/toxic epidermal necrolysis overlap syndrome (0)

Broader categories

Disease (680) Skin disorder (132) Human disease (14) Disease by body system or component (0) Integumentary system disorder (0) Toxic dermatosis (0)

Trials to join now! 3 Not yet recruiting 2 Not yet finished but already full! 1 Completed 6 Terminated 2

Planned study on severe skin reactions withdrawn before starting

Knowledge-focused Terminated

This study was designed to observe and compare different treatments for Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis, severe skin reactions often caused by medications. Researchers planned to track outcomes like healing time and death rates across hospitals using their…

Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused

Last updated Jun 27, 2026 08:11 UTC