Tick-borne infectious disease
MONDO:0025294Bacterial, viral, or parasitic diseases transmitted to humans and animals by the bite of infected ticks. The families Ixodidae and Argasidae contain many bloodsucking species that are important pests of man and domestic birds and mammals and probably exceed all other arthropods in the number and variety of disease agents they transmit. Many of the tick-borne diseases are zoonotic.
Also known as: Tick borne diseases, Tick borne infections, Tick-borne disease, Tick-borne infection, Tick-borne infections, disease, Tick-borne, diseases, Tick-borne, infection, Tick-borne
40 clinical trials for this condition and its sub-types.
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Broader categories
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New antibody shot could shield against Tick-Borne brain virus
Prevention Not yet recruitingThis early-stage study tests a lab-made antibody called TBE025 in 18 healthy adults aged 18 to 55. The goal is to see if it is safe and how the body processes it when given through a vein. Participants receive one dose and are closely monitored for side effects. This research hel…
Phase: PHASE1 • Sponsor: Giuseppe Pantaleo • Aim: Prevention
Last updated Jun 27, 2026 09:00 UTC
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New hope for Tick-Bite survivors: mast cell drugs aim to ease lingering symptoms
Symptom relief Not yet recruitingThis study tests whether medications that calm mast cells (ketotifen and cromolyn) can safely reduce persistent symptoms like fatigue, pain, and brain fog in people who had a tick-borne illness. Fifty adults aged 21-65 will receive either one of these drugs or a standard antihist…
Phase: PHASE2 • Sponsor: University of North Carolina, Chapel Hill • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Could a malaria drug ease lingering lyme symptoms?
Symptom relief Not yet recruitingThis study tests whether adding hydroxychloroquine (a malaria drug) to standard doxycycline treatment can reduce long-term complaints in adults with Lyme disease. Fifty participants will take either hydroxychloroquine or a placebo twice daily for 28 days, with follow-up visits ov…
Phase: PHASE4 • Sponsor: Radboud University Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Immune cell tracking could sharpen lyme disease diagnosis
Knowledge-focused Not yet recruitingThis study explores a new way to diagnose Lyme disease by measuring immune cell responses to the bacteria. Researchers use a technique called flow cytometry to analyze T-cells from patients with a late-stage form of Lyme disease. The goal is to see if this method can tell active …
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
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Hidden Tick-Borne arthritis under investigation in denmark
Knowledge-focused Not yet recruitingThis study aims to find out how common Borrelia arthritis is in Denmark and how it affects patients. Researchers will test blood and joint fluid from 350 adults with joint swelling to look for Borrelia bacteria. Participants will also answer questions about symptoms and tick expo…
Sponsor: Fredrikke Christie Knudtzen • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC