Tardive dyskinesia
MONDO:0010096Also known as: tardive dyskinesia, tardive dyskinesia (disease)
10 clinical trials for this condition and its sub-types.
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Can a drug calm uncontrollable movements? new trial tests tetrabenazine
Disease control CompletedThis Phase 3 trial tested whether tetrabenazine (Xenazine) can reduce involuntary movements in people with tardive dyskinesia, a condition caused by long-term use of antipsychotic medications. Fifty-four adults with persistent symptoms were randomly assigned to receive either tet…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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New drug shows promise in taming tardive dyskinesia movements
Symptom relief CompletedThis study tested a drug called SD-809 (deutetrabenazine) in 298 people with moderate to severe tardive dyskinesia, a condition causing uncontrollable movements. Participants received either the drug or a placebo for 12 weeks. The main goal was to see if the drug reduced the seve…
Phase: PHASE3 • Sponsor: Auspex Pharmaceuticals, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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Valbenazine shows promise for easing involuntary movements in tardive dyskinesia
Symptom relief CompletedThis completed Phase 4 study tested valbenazine in 59 adults with tardive dyskinesia (involuntary muscle movements) caused by psychiatric medications. Participants had schizophrenia, bipolar disorder, or major depression. Over 24 weeks, researchers measured changes in quality of …
Phase: PHASE4 • Sponsor: Neurocrine Biosciences • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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New drug shows promise for taming involuntary movements
Symptom relief CompletedThis study tested a once-daily drug called MT-5199 in 256 adults with tardive dyskinesia, a condition causing uncontrollable movements. The goal was to see if the drug could reduce these movements safely. Participants had mental health conditions like schizophrenia or bipolar dis…
Phase: PHASE2, PHASE3 • Sponsor: Tanabe Pharma Corporation • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC