Synovial sarcoma
MONDO:0010434Synovial sarcoma is an aggressive soft tissue sarcoma, occurring most commonly in adolescents and young adults (15 to 40 years), usually localized near the large joints of the extremities but also in the head and neck, mediastinum and viscera (lung, kidney etc), clinically presenting as a deep seated swelling or a painful mass often with an initial indolent course and is characterized by its local invasiveness and a propensity to metastasize. The origin of synovial sarcoma is likely from multipotent mesenchymal cells and not synovium (contrary to its name).
Also known as: SS, Synovialosarcoma, sarcoma, synovial, malignant, synovial sarcoma, synovial sarcoma (disease), sarcoma, synovial
2863 clinical trials for this condition and its sub-types, 53 tagged with Synovial sarcoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Synovial sarcoma
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Biphasic synovial sarcoma 0 trials
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Breast synovial sarcoma 0 trials
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Fibrous synovial sarcoma 0 trials
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Mediastinum synovial sarcoma 0 trials
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Monophasic synovial sarcoma 0 trials
2 sub-types
- Epithelioid cell synovial sarcoma 0 trials
- Spindle cell synovial sarcoma 0 trials
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Experimental cancer drug LY3405105 fails to advance in early trial
Disease control Stopped earlyThis early-phase study tested the safety of an oral drug called LY3405105 in 54 people with advanced solid tumors. The trial was divided into two parts to find the right dose and to see if the drug could shrink tumors. However, the study was terminated early, meaning the drug did…
Phase 1 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Could a genetic marker guide future cancer therapies in taiwan?
Knowledge-focused Stopped earlyThis study is measuring how often a specific genetic marker (HLA-A*02:01) and a cancer-related protein (NY-ESO-1) appear in Taiwanese patients with solid tumors like head and neck, liver, lung, breast, and esophageal cancers. By understanding these frequencies, researchers hope t…
Sponsor: PharmaEssentia • Aim: Knowledge-focused
Last updated Jul 24, 2026 00:00 UTC