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Supranuclear oculomotor palsy

MONDO:0020257

Oculomotor palsy that arises from lesions in the supranuclear pathways controlling extraocular movement.

Also known as: supranuclear eye movement disorder, conjugate gaze palsy, gaze palsy, supranuclear disorder of eye movement, supranuclear ocular palsy

78 clinical trials for this condition and its sub-types, 0 tagged with Supranuclear oculomotor palsy itself.

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Where it sits in the disease tree

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Part of

↑ Oculomotor nerve paralysis (87)

Sub-types of Supranuclear oculomotor palsy

Progressive supranuclear palsy 74 trials · 78 incl. sub-types
4 sub-types
- Supranuclear palsy, progressive, 1 5 trials
- Atypical progressive supranuclear palsy syndrome 1 trial · 4 incl. sub-types Sub-types →
- Supranuclear palsy, progressive, 2 0 trials
- Supranuclear palsy, progressive, 3 0 trials

Most studied deeper sub-types

Progressive supranuclear palsy-parkinsonism syndrome (2) Progressive supranuclear palsy-corticobasal syndrome (1) Progressive supranuclear palsy-progressive non-fluent aphasia syndrome (0) Progressive supranuclear palsy-pure akinesia with gait freezing syndrome (0)

Including sub-types (78) Tagged with Supranuclear oculomotor palsy (0)

Trials to join now! 34 Not yet recruiting 8 Not yet finished but already full! 18 Completed 17 Terminated 1

Experimental drug aims to curb disinhibition in dementia patients

Symptom relief Stopped early

This study tested a drug called AVP-786 to see if it could safely reduce disinhibition—impulsive or inappropriate behavior—in people with neurodegenerative disorders like Alzheimer's or frontotemporal dementia. The trial planned to include many participants but was terminated ear…

Phase 2 • Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc. • Aim: Symptom relief

Last updated Jun 27, 2026 12:32 UTC