Superior limbic keratoconjunctivitis
MONDO:0019504A chronic and recurrent eye disease which affects the superior bulbar conjunctiva (the clear layer that covers the eyeball, over the sclera) and tarsal conjunctiva (the clear layer that lines the eyelids), as well as the superior limbic aspect of the cornea (the area above the cornea). It is commonly found in women 20-70 years of age. The signs and symptoms include burning, redness and irritation and tend to develop slowly over a period of 1 to 10 years.Vision usually remains intact. While the underlying cause of SLK remains unknown, it is believed that the condition is secondary to superior bulbar conjunctiva laxity. Factors inducing conjunctiva laxity include thyroid eye disease (usually hyperthyroidism), tight upper eyelids, and prominent globes. A mimicking disorder has been encountered in soft contact lens (SCL) wearers, typically with exposure to thimerosal-preserved solutions. Treatment of SLK may involve the use of various medications, surgery, or a combination of both.
Also known as: SLK, Theodore's superior limbic keratoconjunctivitis, Theodore's syndrome, Theodores superior limbic keratoconjunctivitis, Theodores syndrome, superior limbal keratoconjunctivitis
7 clinical trials for this condition and its sub-types.
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Laser before eye implant may prevent glaucoma damage
Disease control Recruiting nowThis study tests whether giving a laser treatment (transscleral cyclophotocoagulation) to lower eye pressure before a Boston keratoprosthesis (a plastic cornea implant) can prevent or slow glaucoma. Twenty adults who need the implant will receive one of two laser types 4-8 weeks …
Phase: NA • Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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German eye registry reveals shifting trends in corneal transplants
Knowledge-focused Recruiting nowThis long-term study collects data from over 100 eye clinics in Germany to see how corneal transplant surgeries have changed since 2001. Researchers track the number of surgeries, the types of procedures used, and the reasons people need them. The goal is to understand trends, no…
Sponsor: Universität des Saarlandes • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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New eye scanner tested on 180 volunteers – no treatment involved
Knowledge-focused Recruiting nowThis study gathers eye scan images from 180 people with healthy eyes or eye diseases like glaucoma and retinal disease. The goal is to collect data using a new optical coherence tomography (OCT) device called A10900. No treatment or medication is given. The information will help …
Sponsor: Optos, PLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC