Spastic paraplegia-nephritis-deafness syndrome
MONDO:0008440This syndrome is characterized by variable spastic paraplegia, bilateral sensorineural deafness, intellectual deficit and progressive nephropathy.
Also known as: Fitzsimmons-Walson-Mellor syndrome, Fitzsimmons Walson Mellor syndrome, spastic paraplegia - nephritis - deafness, spastic paraplegia, bilateral sensorineural deafness, intellectual retardation, and progressive nephropathy, spastic paraplegia, sensorineural deafness, intellectual disability, and progressive nephropathy, spastic paraplegia, sensorineural deafness, mental retardation, and progressive nephropathy
14 clinical trials for this condition and its sub-types.
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Could a zapping cap boost memory? small study tests brain stimulation for cognitive decline
Symptom relief Not yet recruitingThis pilot study will test whether a non-invasive brain stimulation technique called transcranial alternating current stimulation (tACS) can improve working memory in 30 adults with mild cognitive impairment or traumatic brain injury. Participants will receive low-level electrica…
Phase: NA • Sponsor: Sunnybrook Health Sciences Centre • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Gene therapy readiness check: new study maps virus immunity in muscle disease patients
Knowledge-focused Not yet recruitingThis study will test blood samples from 450 people aged 6 to 60 with inherited neuromuscular diseases to see if they have antibodies that could block gene therapy viruses (AAVs). The goal is to understand how common these antibodies are and which patients might be good candidates…
Phase: NA • Sponsor: Genethon • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC