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Severe combined immunodeficiency due to LCK deficiency

MONDO:0014334

Also known as: SCID due to LCK deficiency, SCID due to lymphocyte-specific protein tyrosine kinase deficiency, immunodeficiency type 22, severe combined immunodeficiency due to lymphocyte-specific protein tyrosine kinase deficiency, IMD22, immunodeficiency 22

2 clinical trials for this condition and its sub-types.

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Broader categories

Disease (717) Hereditary disease (188) Immune system disorder (150) Immunodeficiency disease (55) Severe combined immunodeficiency (23) Human disease (15) Combined immunodeficiency (3) Disease of genetic or genomic mechanism (2) Disease by body system or component (0) Disease by etiologic mechanism (0)
Completed 1 Terminated 1
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  • Bubble baby breakthrough? experimental cell shot aims to reboot immune system faster

    Disease control Completed

    This early-phase trial tested whether injecting special immune-building cells (HTLPs) could help children with severe combined immunodeficiency (SCID) rebuild their immune system faster after a partially matched stem cell transplant. Only 4 children took part. The goal was to see…

    Phase 1/2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control

    Last updated Jun 27, 2026 12:36 UTC

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