Severe combined immunodeficiency due to DCLRE1C deficiency

MONDO:0011225

Severe combined immunodeficiency (SCID) due to DCLRE1C deficiency is a type of SCID characterized by severe and recurrent infections, diarrhea, failure to thrive, and cell sensitivity to ionizing radiation.

Also known as: DCLRE1C severe combined immunodeficiency (disease), SCID due to ARTEMIS deficiency, SCID due to DCLRE1C deficiency, SCID due to artemis deficiency, SCID, Athabascan type, SCID, Athabaskan type, severe combined immunodeficiency (disease) caused by mutation in DCLRE1C, severe combined immunodeficiency due to ARTEMIS deficiency

42 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Metabolic disease (215) Hereditary disease (172) Immune system disorder (140) Immunodeficiency disease (48) Inborn errors of metabolism (42) Severe combined immunodeficiency (21) Human disease (14) DNA repair disease (11) Combined immunodeficiency (3)

Trials to join now! 23 Not yet recruiting 3 Not yet finished but already full! 5 Completed 10 Terminated 1

New stem cell method aims to protect kids with rare immune disease

Disease control Terminated

This study tested a way to improve stem cell transplants for children with combined immunodeficiency (CID), a condition where the immune system doesn't work properly. The approach removed certain naive cells from the donor stem cells to try to prevent graft-versus-host disease (a…

Phase: PHASE2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control

Last updated Jun 27, 2026 12:02 UTC

Severe combined immunodeficiency due to DCLRE1C deficiency

Broader categories

New stem cell method aims to protect kids with rare immune disease