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Scleromyxedema without monoclonal gammopathy

MONDO:0019585

Scleromyxedema without monoclonal gammopathy is a form of atypical lichen myxedematosus, characterized by a generalized sclerodermoid infiltration of skin studded with multiple, firm papules of 1-3 mm in diameter involving face (leonine appearance), trunk, and limbs, without monoclonal gammopathy. The involvement of the face can be missing and pruritus may be prominent.

7 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Skin disorder (123) Human disease (14) Cutaneous mucinosis (1) Atypical lichen myxedematosus (0) Dermis disorder (0) Disease by body system or component (0) Integumentary system disorder (0) Lichen myxedematosus (0)
Trials to join now! 4 Not yet recruiting 1 Not yet finished but already full! 1 Completed 1
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  • AI vs. skin doctors: who diagnoses better?

    Knowledge-focused ENROLLING_BY_INVITATION

    This study looks at whether artificial intelligence (AI) can match a dermatologist's diagnosis when a general practitioner sends in photos and questions about a patient's skin condition. Researchers will compare the AI's diagnosis to the dermatologist's for about 1000 adults. The…

    Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused

    Last updated Jun 27, 2026 08:11 UTC

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